When Shaul Massry and Herbert Fleisch asked me to write a foreword
for this book, I was honored and eagerly looked forward to reading
the many chapters. As they came and I skimmed through them, my mind
wandered back to the earliest classic contributions in this field
in the late 1920s and early 1930s by Albright and his associates,
Greenwald and Gross and Adolph, on the homeostatic regulation of
inorganic phosphate and the central role of parathyroid hormone
(PTH) in this regulation. They clearly showed the exquisite
sensitivity of the renal handling of phosphate to varying dietary
and parenteral loads and to changes in the level ofPTH. That two
outstanding investigators in the field of divalent ion me tabolism
should choose to edit a book solely about the renal handling of
inorganic phosphate shows how far we have progressed from these
early classics to the recent almost exponential increase in the
research and publications related to this subject. Despite this
increase, I asked myself, is such a large new monograph, consisting
of 13 chapters and 30 distin guished authors, warranted? My reading
of these chapters and my learning so much from them convinced me
that it is, and my pride was heightened in being asked to write the
foreword for this book."
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