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First in Fly - Drosophila Research and Biological Discovery (Hardcover)
Loot Price: R870
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First in Fly - Drosophila Research and Biological Discovery (Hardcover)
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A single species of fly, Drosophila melanogaster, has been the
subject of scientific research for more than one hundred years. Why
does this tiny insect merit such intense scrutiny? Drosophila's
importance as a research organism began with its short life cycle,
ability to reproduce in large numbers, and easy-to-see mutant
phenotypes. Over time, laboratory investigation revealed surprising
similarities between flies and other animals at the level of genes,
gene networks, cell interactions, physiology, immunity, and
behavior. Like humans, flies learn and remember, fight microbial
infection, and slow down as they age. Scientists use Drosophila to
investigate complex biological activities in a simple but intact
living system. Fly research provides answers to some of the most
challenging questions in biology and biomedicine, including how
cells transmit signals and form ordered structures, how we can
interpret the wealth of human genome data now available, and how we
can develop effective treatments for cancer, diabetes, and
neurodegenerative diseases. Written by a leader in the Drosophila
research community, First in Fly celebrates key insights uncovered
by investigators using this model organism. Stephanie Elizabeth
Mohr draws on these "first in fly" findings to introduce
fundamental biological concepts gained over the last century and
explore how research in the common fruit fly has expanded our
understanding of human health and disease.
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