"Cancer Drug Design and Discovery, Second Edition" is an
important reference on the underlying principles for the design and
subsequent development of new anticancer small molecule agents. New
chapters have been added to this edition on areas of particular
interest and therapeutic promise, including cancer genomics and
personalized medicine, DNA-targeted agents and more. This book
includes several sections on the basic and applied science of
cancer drug discovery and features those drugs that are now
approved for human use and are in the marketplace, as well as those
that are still under development. By highlighting some of the
general principles involved in taking molecules through basic
science to clinical development, this book offers a complete and
authoritative reference on the design and discovery of anticancer
drugs for translational scientists and clinicians involved in
cancer research.
Provides a clinical perspective on the development of new
molecularly targeted anticancer agents with the latest and most
promising chemotherapeutic approachesOffers a broad view of where
the field is going, what tools drug discovery is using to produce
new agents and how they are evaluated in the laboratory and
clinicFeatures 6 new chapters devoted to advances in technology and
successful anticancer therapies, such as cancer genomics and
personalized medicine, DNA-targeted agents, B-Raf inhibitors and
moreEach chapter includes extensive references to the primary and
review literature, as well as to relevant web-based sources"
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