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The World of Peptides - A Brief History of Peptide Chemistry (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R3,286
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The World of Peptides - A Brief History of Peptide Chemistry (Paperback, Softcover reprint of the original 1st ed. 1991)
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Almost two centuries ago proteins were recognized as the primary
materials (proteios = primary) oflife, but the significance and
wide role of peptides (from pepsis = digestion) in practically all
life pro cesses has only become apparent in the last few decades.
Biologi cally active peptides are now being discovered at rapid
intervals in the brain and in other organs including the heart, in
the skin of amphibians and many other tissues. Peptides and
peptide-like compounds are found among toxins and antibiotics. It
is unlikely that this process, an almost explosive broadening of
the field, will come to a sudden halt. By now it is obvious that
Nature has used the combination of a small to moderate number of
amino acids to generate a great variety of agonists with specific
and often highly sophisticated functions. Thus, peptide chemistry
must be regarded as a discipline in its own right, a major branch
of biochemistry, fairly separate from the chemistry of proteins.
Because of the important role played by synthesis both in the study
and in the practical preparation of peptides, their area can be
considered as belonging to bio-organic chemistry as well. The
already overwhelming and still increasing body of know ledge
renders an account of the history of peptide chemistry more and
more difficult. It appears therefore timely to look back, to take
stock and to recall the important stages in the development of a
new discipline."
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