Epigenetics in Human Disease, Third Edition examines the diseases
and conditions on which we have advanced knowledge of epigenetic
mechanisms, such as cancer, autoimmune disorders, aging, metabolic
disorders, neurobiological disorders and cardiovascular disease.
From molecular mechanisms and epigenetic technology to clinical
translation of recent research, the nature and applications of the
science is presented for those with interests ranging from the
fundamental basis of epigenetics to therapeutic interventions for
epigenetic-based disorders, with an emphasis throughout on
understanding and application of key concepts in new research and
clinical practice. Fully revised and up-to-date, this Third Edition
discusses topics of current interest in epigenetic disease
research, including stem cell epigenetic therapy, bioinformatic
analysis of NGS data, epigenetic mechanisms of imprinting
disorders, microRNA in cancer, epigenetic approaches to control
obesity, epigenetics and airway disease, and epigenetics in
cardiovascular disease. Further sections explore online epigenetic
tools and datasets; early-life programming of epigenetics in
age-related diseases; the epigenetics of addiction and suicide, and
epigenetic approaches to regulating and preventing diabetes,
cardiac disease, allergic disorders, Alzheimer’s disease,
respiratory diseases, and many other human maladies. In addition,
each chapter now includes chapter summaries, definitions, and
vibrant imagery and figures to reinforce understanding, as well as
step-by-step methods and disease research case studies.
General
| Imprint: |
Academic Press Inc
|
| Country of origin: |
United States |
| Series: |
Translational Epigenetics |
| Release date: |
September 2023 |
| First published: |
2024 |
| Editors: |
Trygve O Tollefsbol
|
| Dimensions: |
234 x 191mm (L x W) |
| Pages: |
1300 |
| Edition: |
3rd edition |
| ISBN-13: |
978-0-443-21811-8 |
| Categories: |
Books
|
| LSN: |
0-443-21811-0 |
| Barcode: |
9780443218118 |
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