Contagious Caprine pleuropneumonia (CCPP) is major threat to goat
population world wide particularly in African countries, Middle
East and subcontinent including Pakistan and Afghanistan. CCPP is
caused by Mycoplasma mycoides cluster consist of six different spp
having different lethal outcome. The diagnosis of this fatal
disease is very difficult due to several constrains. The present
study provides valuable information for the rapid and accurate
diagnosis of this disease for both veterinary professional and
researchers. PCR technique is more reliable and sensitive tools for
diagnosis of CCPP. The Mycoplasma mycoides capri was isolated and
identified from lungs tissues of infected goats. The disease was
efficiently reproduced in experimental animals that adopted acute
septicemic form with lethal outcomes. Immunohistochemical technique
was first time optimized in Pakistan for detection of antigen
within the tissues. The findings of this study will paved way for
the preparation of vaccine from the field strain that would be used
for effective eradication of this devastating disease from the goat
population.
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