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G Protein-Coupled Receptor Kinases (Hardcover, 1st ed. 2016)
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G Protein-Coupled Receptor Kinases (Hardcover, 1st ed. 2016)
Series: Methods in Pharmacology and Toxicology
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This collection explores up-to-date descriptions of known G
protein-coupled receptor kinase (GRK)-dependent mechanisms, both
associated with G protein-coupled receptor (GPCR) functions and the
receptor-independent. The chapters cover a wide range of studies
from invertebrates to humans, with sections of the volume covering
GRK structure, mechanisms of activation, and interaction with
GPCRs, GRKs in cell signaling, as well as physiological and
pathophysiological mechanisms regulated by GRKs. Written for the
Methods in Pharmacology and Toxicology series, this book features
the kind of practical detail necessary for success in the
laboratory. Authoritative and timely, G Protein-Coupled Receptor
Kinases features the kind of comprehensive mechanistic elucidation
of GRK functions and their regulation in cells necessary for a
better understanding of cell biology as well as for devising novel
research approaches and therapeutic strategies.
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