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Manual of Biological Markers of Disease (Paperback, Softcover reprint of the original 1st ed. 1996)
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Discovery Miles 16 720
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Manual of Biological Markers of Disease (Paperback, Softcover reprint of the original 1st ed. 1996)
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Section A: Methods of Autoantibody Detection This Section provides
well structured protocols for autoantibody detection. Step-by-step
procedures are accompanied by explanatory notes and comments, clear
diagrams, line illustrations and excellent photo illustrations.
Extensive literature references lead the way to further background
information. The methods presented were validated by more than 40
leading laboratories active in sera analysis, which indicates that
these methods have been found to be practically useful and lead to
consistent inter-laboratory results: consensus in autoantibody
detection. Section B: Autoantigens This Section contains the first
compilation of full, detailed information on autoantigens related
to important autoimmune diseases. The chapters are all structured
according to an easy-reference fixed template structure: specific
detection methods, cellular localization, biochemical
characteristics, function, cDNA and derived amino acid sequence,
gene structure, B- and T-cell epitopes and lists of published
monoclonal antibodies. The text is greatly enhanced by many
beautiful schematic figures and photo illustrations. As in Section
A, extensive literature references are provided. The information
for this section was brought together by leading experts in their
fields. This Manual is an ideal text and reference book for bench
scientists working in the field of autoimmunity, but also for
rheumatologists, general (internal medicine) physicians or clinical
immunologists caring for patients with autoimmune disorders.
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