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The Heart in Rheumatic, Autoimmune and Inflammatory Diseases - Pathophysiology, Clinical Aspects and Therapeutic Approaches (Hardcover)
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The Heart in Rheumatic, Autoimmune and Inflammatory Diseases - Pathophysiology, Clinical Aspects and Therapeutic Approaches (Hardcover)
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The prevalence of autoimmune diseases and rheumatic conditions is
constantly increasing. Autoimmune diseases affect approximately
7-10% of the population of the United States, while more than
50,000,000 American adults suffer from some type of arthritis. The
Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines
the complex mechanisms relating to cardiac diseases from a
pathophysiological and clinical point of view. Autoimmune rheumatic
diseases can affect the coronary vessels, myocardium, pericardium,
heart valves and the conduction system. The diagnosis of these
unique cardiac complications necessitates medical awareness and a
high index of suspicion. Increased risk of advanced atherosclerosis
plays a pivotal role in the development of cardiac diseases in
systemic, rheumatic and autoimmune illnesses. Yet, other complex
immune medicated mechanisms may contribute to the pathogenesis.
Patients' optimal care requires coordination between the primary
caregiver, the rheumatologist, immunologist and cardiologist.
Screening for cardiovascular risk factors, recognition of high-risk
patients and identification of subclinical cardiac conditions are
of great importance. Moreover, regulation of inflammation, as well
as abnormal immune responses and the initiation of early treatments
should be the focus of patient management. A continuous attempt to
identify novel therapeutic targets and change the natural history
of the underlying disease and its cardiac manifestations is in
progress. The book aims at providing the readers with a state of
the art collection of up to date information regarding clinically
important topics based on experts' perspectives. This book was a
result of an extended coordinated collaboration of one-hundred and
fifty-four distinguished scientists from thirty-one countries
around the globe.
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