Modeling of Post-Myocardial Infarction - ODE/PDE Analysis with R (Paperback)

Modeling of Post-Myocardial Infarction: ODE/PDE Analysis with R presents mathematical models for the dynamics of a post-myocardial (post-MI), aka, a heart attack. The mathematical models discussed consist of six ordinary differential equations (ODEs) with dependent variables Mun; M1; M2; IL10; Ta; IL1. The system variables are explained as follows: dependent variable Mun = cell density of unactivated macrophage; dependent variable M1 = cell density of M1 macrophage; dependent variable M2 = cell density of M2 macrophage; dependent variable IL10 = concentration of IL10, (interleuken-10); dependent variable Ta = concentration of TNF-a (tumor necrosis factor-a); dependent variable IL1 = concentration of IL1 (interleuken-1). The system of six ODEs does not include a spatial aspect of an MI in the cardiac tissue. Therefore, the ODE model is extended to include a spatial effect by the addition of diffusion terms. The resulting system of six diffusion PDEs, with x (space) and t (time) as independent variables, is integrated (solved) by the numerical method of lines (MOL), a general numerical algorithm for PDEs.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Release date:	September 2023
First published:	2024
Authors:	William E. Schiesser
Dimensions:	235 x 191mm (L x W)
Format:	Paperback
Pages:	200
ISBN-13:	978-0-443-13611-5
Categories:	Books
LSN:	0-443-13611-4
Barcode:	9780443136115

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