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The Great Ulcer War (Paperback)
Loot Price: R576
Discovery Miles 5 760
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The Great Ulcer War (Paperback)
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Loot Price R576
Discovery Miles 5 760
Expected to ship within 10 - 15 working days
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In 1983, in Australia, a medical resident, Dr. Barry Marshall, and
a hospital pathologist, Dr. Robin Warren, reported in two letters
to The Lancet finding a bacterium associated with gastritis or
inflammation of the stomach. The publication stimulated little
reaction. However, a year later when they reported that the
bacterium was also associated with ulcer disease and declared that
bacteria caused ulcer disease, it had the effect of an
assassination of an archduke. Most prominent clinical investigators
in the United States and England argued that hyper secretion of
acid was the cause of ulcer disease, and they collaborated with the
pharmaceutical companies that made the new drugs that blocked acid
secretion to attack the new bacterial theory. The Great Ulcer War
tells how the war was fought, the weapons used, and the alliances
made, and why the war in spite of overwhelming evidence in favor of
the bacterial theory, lasted for ten years. The Great Ulcer War
introduces a novel theory, the Pandora Hypothesis, to explain the
length of the war. It proposes that the general medical
establishment especially in the United States simply did not like
the bacterial theories of major chronic diseases. These thought
leaders-"the big guys"-facilitated and prolonged the opposition to
the bacterial theory of ulcers largely by doing nothing to support
the theory until the very end of the war. They were afraid that if
a germ theory was accepted for ulcers, a Pandora's Box of germ
theories developed within university departments of microbiology
for other chronic diseases would be opened and released into the
medical world. This revelation would diminish the reputation and
profit of the medical establishment and the pharmaceutical industry
by threatening their favored explanations of the causes of these
diseases: genomic errors and dysfunctional biochemistry and
physiology.
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