This SpringerBrief explores unconventional functions of eight
different transcription factors and concludes with a discussion
of their biological significance and impact, including
effects on processes within the cell nucleaus during development
and in adult organisms. Chapter One
details unconventional functions of the transcription
factors GAGA, HP1, Rb, STAT, ATF-2 and NF-kB.Â
Surprisingly, all of these transcription factors can be found in
association with heterochromatin as well as euchromatin, and in
some cases unconventional functions have been demonstrated for
these heterochromatin-associated factors. Chapter Two focuses
on the unconventional functions of STAT and HP1 and discusses
their roles in the promotion of longevity, and in protection
from cancer and DNA damage. Chapter Three explores the
biological significance of the findings presented in the first two
chapters and considers how global changes in the epigenome
brought about by factors such as STAT and HP1 might affect
processes within the cell nucleus during development and in adult
organisms. This succinct yet thorough SpringerBrief is
essential for researchers studying epigenetics, and to
instructors of the subject. It should also appeal to people
interested in the control of gene transcription and other processes
in the cell nucleus, and to those interested in development.
General
Imprint: |
Springer International Publishing AG
|
Country of origin: |
Switzerland |
Series: |
SpringerBriefs in Biochemistry and Molecular Biology |
Release date: |
April 2023 |
First published: |
2023 |
Authors: |
Willis X. Li
• Louise Silver-Morse
|
Dimensions: |
235 x 155mm (L x W) |
Pages: |
45 |
Edition: |
1st ed. 2023 |
ISBN-13: |
978-3-03-129027-5 |
Categories: |
Books
|
LSN: |
3-03-129027-5 |
Barcode: |
9783031290275 |
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