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Functional Neuroimaging Methods and Frontiers (Paperback)
Loot Price: R2,632
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Functional Neuroimaging Methods and Frontiers (Paperback)
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Medical imaging grows to be a broad and modern scientific field.
Imaging principles, methods and applications are important topics
in this field. While applications and the generalization of
techniques start with and rely on theoretical development and novel
methodology, introduction and instructions of relatively new ideas,
concepts and methods are of pivotal importance to students,
beginners and general clinical practitioners in this field.
Functional MRI (fMRI) has been widely used for the past 30 years to
investigate brain functional changes under physiologic challenges
or disease conditions in contrast to a resting state. The
physiological contributors to the fMRI signal changes include the
blood-oxygenation-dependent level (BOLD) effect and in-flow effect
such as the increment in local CBF and arterial oxygenation.
Improvement of spatiotemporal resolution of fMRI to enhance
neuronal activity specificity and pinpoint the microvasculature
activation is the ultimate goal. fMRI functional
activity/connectivity and graph theory-based connectome analyses
with a multiplex fast imaging technique are recently developed new
techniques to provide both a whole-picture and regional
specialization of brain resource utilization in a systematic way.
The integration of neuroscience and mathematical as well as
physical and physiological metrics also promote the innovation and
applications of multi-modal imaging equipment development and
multi-parametric utilizations in clinical environments, including
disease diagnosis and treatment. The aim of this book is intended
to provide a whole picture of new fMRI imaging methodological
developments from principles to applications, to both beginners and
experts in biomedical imaging and healthcare. Several fundamental
principles and metrics including BOLD, microvasculature detection
and fMRI/EEG coupling will be presented together with some new and
up-to-date analytical methods. The conventional statistical methods
and relatively new methods of wavelets, dynamic linear correlation
coefficients, independent component analysis, EEG source imaging
and multi-modal integration will be covered. The authors hope that
this book will capture the interests of colleagues in the medical
imaging field and could help convey the methodological, technical
and developmental resources of neuroimaging applications. This book
will provide the current state-of-the-art and frontiers of
neuroimaging techniques in basic science and clinical neuroscience
research. The authors will present some forefront and interesting
multi-dimensional imaging techniques to serve as a textbook and
reference manual in fMRI methodological training as well as in the
research field. Several distinct imaging perspectives, including
cutting-edge imaging methods from acquisition to data analysis as
well as multi-modal and multi-parametric quantifications will be
described. The relatively new and advanced principles and methods
together with interesting examples and application demonstrations
would hopefully contribute to the medical imaging teaching and
research field and could help facilitate the generalization,
interpretation and applications of the proposed neuroimaging
methods.
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