Vincent Cassel stars in this Australian thriller directed and co-written by Ariel Kleiman. Told from the perspective of 11-year-old Alexander (Jeremy Chabriel), the story follows the lives of a group of young children who have been raised in a closed community led by self-elected patriarch Gregori (Cassel). As he trains the children to become assassins, Gregori finds himself increasingly power-hungry sending the children out to kill people on his list. As Alexander's training progresses, he begins to doubt Gregori's rule and decides to challenge his authority the only way he knows how...

Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Diseases presents an excellent resource for surgical residents, hepatobiliary fellows and practicing surgeons interested in hepatobiliary surgery. This textbook offers a readable, concise and practical alternative. It is divided into three sections: liver, biliary tract, and pancreatic diseases. Each section covers the spectrum of benign and malignant disease. In addition, several chapters in each section are devoted to surgical techniques. This textbook should ultimately serve as an essential source for the rapidly evolving field of hepatobiliary surgery and its practitioners.

This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). The authors show that this barrier is crucial for maintaining important compositional differences between the blood plasma and the CSF. The choroid plexus epithelial cells also prevent the spread of infectious agents and other blood-borne entities to the brain tissue. Chapter topics range from the production of CSF by electrolyte regulation in the choroid plexus, to details on the selectively transporting nature of this barrier. Further, the authors elaborate on the important roles of CSF in sustaining brain health by providing hydration, solutes, and nutrients to the brain tissue. Readers will also learn how CSF circulates signaling molecules within the compartments of the brain and removes waste products from the brain tissue. Elucidating the regulation of these processes in the choroid plexus is not only important for the readers' understanding of normal brain development and function, but is also crucial for resolving a variety of cerebral challenges that lead to brain edema, as well as developing treatments for diseases. The book discusses disease models like hydrocephalus, sleep disorders, and age-related dementia. Its comprehensive coverage makes this volume a valuable resource for researchers in cell and neurophysiology, as well as graduate students of the neurosciences.

Johannes G. de Vries: Pd-catalyzed coupling reactions.- Gregory T. Whiteker and Christopher J. Cobley: Applications of Rhodium-Catalyzed Hydroformylation in the Pharmaceutical, Agrochemical and Fragrance Industries.- Philippe Dupau: Ruthenium-catalyzed Selective Hydrogenation for Flavor and Fragrance Applications.- Hans-Ulrich Blaser, Benoit Pugin and Felix Spindler: Asymmetric Hydrogenation.- Ioannis Houpis: Case Study: Sequential Pd-catalyzed Cross-Coupling Reactions; Challenges on Scale-up.- Adriano F. Indolese: Pilot Plant Scale Synthesis of an Aryl-Indole - Scale up of a Suzuki Coupling.- Per Ryberg: Development of a Mild and Robust Method for Palladium Catalysed Cyanation on Large Scale.- Cheng-yi Chen: Application of Ring Closing Metathesis Strategy to the Synthesis of Vaniprevir (MK-7009), a 20-Membered Macrocyclic HCV Protease Inhibitor.

Indigenous peoples today are enmeshed in the expanding modern economy, subject to the pressures of both market and government. This book takes indigenous peoples as actors, not victims, as its starting point in analysing this interaction. It assembles a rich diversity of statements, case studies and wider thematic explorations, primarily from North America, and particularly the Cree, the Haudenausaunee (Iroquois) and Chippewa-Ojibwe peoples who straddle the US/Canadian border, but also from South America and the former Soviet Union. It explores the complex relationships between indigenous peoples, civil society, and the environment. It shows how the boundaries between indigenous peoples' organizations, civil society, the state, markets, development and the environment are ambiguous and constantly changing. These complexities create both opportunities and threats for local agency. People resist or react to the pressures of market and state, while sustaining 'life projects' of their own, embodying their own local history, visions and strategies.

This volume is the fourth in a series designed to facilitate inter-disciplinary communication between scientists concerned with the description of societal phenomena and those investigating adult development. As such, it contains a compilation of papers presented at an annual conference held at the Pennsylvania State University. These essays by sociologists and epidemiologists deal with the impact of disease and health outcomes with advancing age and are critiqued by members of related disciplines. In addition, there are overviews as well as specific discussions about the impact of cancer, depression, and cardiovascular diseases upon psychosocial functions.

This second edition of the pioneering work on this hot topic captures the major trends and latest achievements in the art of asymmetric catalysis on an industrial scale. A number of completely new real-life case studies written by the world leaders in their respective areas provide a compact and qualified insight into this developing field. The resulting ready reference and handbook collates first-hand and valuable information within a context where it can be easily found.
The high-quality contributions illustrate the relevant environments and situations, such as time pressure, how the catalytic step fits into the overall synthesis, or competition with other synthetic approaches, as well as the typical problems encountered in the various phases, including finding/developing the catalyst and optimization of the process or choice of equipment. Both successful and unsuccessful approaches to solve these problems are described.

This volume is the fourth in a series designed to facilitate inter-disciplinary communication between scientists concerned with the description of societal phenomena and those investigating adult development. As such, it contains a compilation of papers presented at an annual conference held at the Pennsylvania State University. These essays by sociologists and epidemiologists deal with the impact of disease and health outcomes with advancing age and are critiqued by members of related disciplines. In addition, there are overviews as well as specific discussions about the impact of cancer, depression, and cardiovascular diseases upon psychosocial functions.

A clarion call to save humanity's most essential fellow creatures - and our health Far beneath our skin exists an unfathomable, ancient universe - an internal ecosystem that is critical to our health. Dr Martin Blaser invites us into the wilds of the human 'microbiome', unfurling its inner workings and evolution. For thousands of years, bacteria and human cells have co-existed in a relationship that has ensured the health and equilibrium of our body. But now, much like the natural world outside of us, our internal environment is being irrevocably destroyed. The culprit: some of our most revered medical advances - antibiotics - which appear to be linked to the epidemics of asthma, eczema, obesity, certain forms of cancer, and other diseases plaguing modern society. In a book that stands as the Silent Spring of its day, Blaser sounds a provocative alarm that we ignore at our peril.

Depression has become the most frequently diagnosed chronic mental illness, and is a disability encountered almost daily by mental health professionals of all trades. "Major Depression" is a medical disease, which some would argue has reached epidemic proportions in contemporary society, and it affects our bodies and brains just like any other disease. Why, this book asks, has the incidence of depression been on such an increase in the last 50 years, if our basic biology hasn't changed as rapidly? To find answers, Dr. Blazer looks at the social forces, cultural and environmental upheavals, and other external, group factors that have undergone significant change. In so doing, the author revives the tenets of social psychiatry, the process of looking at social trends, environmental factors, and correlations among groups in efforts to understand psychiatric disorders.

Clinical Manual of Geriatric Psychiatry provides the most current information on psychiatric diagnoses seen in older patients in a concise format. Each chapter is broken into easily understandable, increasingly focused sections, and contains an extensive array of tables, references, and suggested readings. Chapters include clinically relevant information and evidence-based treatments for a wide range of topics and disorders: * The psychiatric interview of older adults, including history, family assessment, mental status examination, rating scales and standardized interviews, and effective communication techniques.* Psychopharmacology, including information on antidepressants, psychostimulants, antipsychotic medications, mood stabilizers, anxiolytics and sedative-hypnotics, and cognitive enhancers.* Diagnosis and treatment of delirium, dementia, mood disorders, schizophrenia, anxiety disorders, sleep disorders, and substance use disorders, including coverage of definition, epidemiology, clinical features, risk factors, diagnosis and differential diagnosis, prevention and management, and treatment guidelines.* Individual and group psychotherapy strategies, including individual and group-based cognitive-behavioral therapies, interpersonal psychotherapies, relaxation training, cognitive stimulation therapy, and behavioral therapies.* Clinical psychiatry in the nursing home, with a focus on cognitive disorders and behavioral disturbances, depression, treatment progress in this setting, and relevant federal regulations. Written by experts in geriatric psychiatry, this clinical manual provides a much-needed "field guide" for the care of nursing home patients and older adults. Busy clinicians, as well as researchers, residents, fellows, clinical psychologists, and social workers, will find this compact volume to be of the utmost value, as will anyone seeking to update their knowledge of geriatric psychiatry.

Depression has become the most frequently diagnosed chronic mental illness, and is a disability encountered almost daily by mental health professionals of all trades. Major depression is a medical disease, which some would argue has reached epidemic proportions in contemporary society, and it affects our bodies and brains just like any other disease. The Age of Melancholy asks why the incidence of depression has been on such an increase in the last 50 years, if our basic biology hasn't changed as rapidly. To find answers, Dr. Blazer looks at the social forces, cultural and environmental upheavals, and other external, group factors that have undergone significant change. In so doing, the author revives the tenets of social psychiatry, the process of looking at social trends, environmental factors, and correlations among groups in efforts to understand psychiatric disorders. The biomedical model of psychiatry that has dominated the field for the past half-century has faced minimal scrutiny, due in part to the apparent advances made in the treatment of mental health issues during that time. But, Dr. to complement and complete the model, and he points to two concurrent trends for support: during the same 50-year period that saw the death of social psychiatry, the rate of occurrence and increasing medicalization of depression as a secluded individual's issue have brought us to the Prozac era. In making the case for the connection of these two trends (both the products themselves of larger social and cultural movements), the author proposes a return of a new, more mature social psychiatry, to complete - not replace - the biomedical and clinical research models in place today. This book is eminently readable, and should appeal to a broader audience than the psychiatrists, clinicians, and researchers who will make up the primary audience. While replete with the standard mental health references, sound research, and authored by a recognized and respected professional, the ease of language and range of examples make this text accessible to a lay reader. This book should have cross-over appeal in sociology as well as social work and psychology.

This book highlights the importance of the choroid plexus, which forms the blood-cerebrospinal fluid barrier and is the site of the major production of the cerebrospinal fluid (CSF). The authors show that this barrier is crucial for maintaining important compositional differences between the blood plasma and the CSF. The choroid plexus epithelial cells also prevent the spread of infectious agents and other blood-borne entities to the brain tissue. Chapter topics range from the production of CSF by electrolyte regulation in the choroid plexus, to details on the selectively transporting nature of this barrier. Further, the authors elaborate on the important roles of CSF in sustaining brain health by providing hydration, solutes, and nutrients to the brain tissue. Readers will also learn how CSF circulates signaling molecules within the compartments of the brain and removes waste products from the brain tissue. Elucidating the regulation of these processes in the choroid plexus is not only important for the readers' understanding of normal brain development and function, but is also crucial for resolving a variety of cerebral challenges that lead to brain edema, as well as developing treatments for diseases. The book discusses disease models like hydrocephalus, sleep disorders, and age-related dementia. Its comprehensive coverage makes this volume a valuable resource for researchers in cell and neurophysiology, as well as graduate students of the neurosciences.

When sports ministry first emerged in the 1950s and 1960s, its founders imagined male celebrity athletes as powerful salespeople who could deliver a message of Christian strength: "If athletes can endorse shaving cream, razor blades, and cigarettes, surely they can endorse the Lord, too," reasoned Fellowship of Christian Athletes founder Don McClanen. But combining evangelicalism and sport did much more than serve as an advertisement for religion: it gave athletes the opportunity to think about the embodied experiences of sport as a way to experience intimate connection with the divine. As sports ministry developed, it focused on individual religious experiences and downplayed celebrity sales power, opening the door for female Christian athletes to join and eventually dominate sports ministry. Today, women are the majority of participants in sports ministry in the United States. In Playing for God, Annie Blazer offers an exploration of the history and religious lives of Christian athletes, showing that evangelical engagement with popular culture can carry unintended consequences. When sport became an avenue for embodied worship, it forced a reckoning with evangelical teachings about the body. Female Christian athletes increasingly turned to their own bodies to understand their religious identity, and in so doing, came to question evangelical mainstays on gender and sexuality. What was once a male-dominated masculinist project of sports engagement became a female-dominated movement that challenged evangelical ideas on femininity, marriage hierarchy, and the sinfulness of homosexuality. Though evangelicalism has not changed sporting culture, for those involved in sports ministry, sport has changed evangelicalism.

Johannes G. de Vries: Pd-catalyzed coupling reactions.- Gregory T. Whiteker and Christopher J. Cobley: Applications of Rhodium-Catalyzed Hydroformylation in the Pharmaceutical, Agrochemical and Fragrance Industries.- Philippe Dupau: Ruthenium-catalyzed Selective Hydrogenation for Flavor and Fragrance Applications.- Hans-Ulrich Blaser, Benoit Pugin and Felix Spindler: Asymmetric Hydrogenation.- Ioannis Houpis: Case Study: Sequential Pd-catalyzed Cross-Coupling Reactions; Challenges on Scale-up.- Adriano F. Indolese: Pilot Plant Scale Synthesis of an Aryl-Indole - Scale up of a Suzuki Coupling.- Per Ryberg: Development of a Mild and Robust Method for Palladium Catalysed Cyanation on Large Scale.- Cheng-yi Chen: Application of Ring Closing Metathesis Strategy to the Synthesis of Vaniprevir (MK-7009), a 20-Membered Macrocyclic HCV Protease Inhibitor.

The Romanistische Arbeitshefte (Romance Studies Workbooks), edited by Georgia Veldre-Gerner and Volker Noll since 2004, have been constant and reliable companions for students of Romance Studies for fifty years. In their conception, they are designed as a reflection of the present state of research with an orientation towards application and the specific needs and difficulties of students. Thus they provide a reliable instrument for getting to grips with various areas of Romance linguistic studies and encourage students to utilise their newly-acquired knowledge with integrated exercises.

"The book is very effective in communicating the many aspects, dimensions and interpretations of sustainable forest management (SFM)...It is clearly born out of an ambitious remit to present an overview of SFM across all its dimensions. In this, it is by and large successful... It provides an effective entry into almost any SFM topic." Review in Scottish Forestry by Professor Jaboury Ghazoul, ETH Zurich/University of Edinburgh "Achieving Sustainable Management of Tropical Forests provides an excellent and essential read for those with responsibility for managing the world's tropical forests...The editors, Dr Blaser and Dr Hardcastle, are to be congratulated for editing the chapters into a very consistent read... Each chapter is authored by an expert or experts in the particular geography and/or discipline as social, governance, tenure, biology, rural livelihoods, climate change, products etc." Journal of Forestry - Society of American Foresters Although global rates of deforestation have started to decrease, they remain alarmingly high in many tropical countries. In light of this challenge, the growing importance of sustainable forest management (SFM) has been highlighted as a means for improving sustainability across the sector. Achieving sustainable management of tropical forests summarises and reviews the rich body of research on tropical forests and how this research can be utilised to make sustainable management of tropical forests a standard implementable strategy for the future. The book features expert discussions on the economic, political and environmental contexts needed for SFM to operate successfully, including coverage of the UN's Sustainable Development Goals (SDGs). With its distinguished editors and international array of expert authors, Achieving sustainable management of tropical forests will be a standard reference for researchers in tropical forest science, international and national organisations responsible for protection and responsible stewardship of tropical forests, as well as the commercial sector harvesting and using tropical forest products.

This volume contains 14 survey articles by reputed database researchers. They give an account of the state of the art, present research highlights and offer an outlook into the '90s regarding the most likely evolution of database technology-research, ad-tech, products and applications. The volume is structured into the following parts: - The evolution of database technology and its impact on enterprise information systems (keynote paper); - Demands on database systems in the '90s (office, engineering, science, multimedia, standardization); - User aspects (application programmers, ad hoc query users); - Database system and architecture concepts for novel applications (data models, object orientation, deductive DBMS, extensibility, data replication); - System and implementation aspects (performance and reliability, distributed and cooperative DBMS, hardware impact). The volume may serve as an orientation for all those who are interested in database systems and their impact on computer applications.

Derzeit verfugbare "universelle" Datenbanksysteme sind historisch fur betriebswirt- schaftliche Anwendungen entst&lden. In Anwendungsgebieten wie der Unterstutzung von Burotatigkeiten oder der rechnergestutzten Konstruktion und Fertigung (CAD/CAM - CIM) stossen sie daher vielfach Rn die Grenzen ihrer Fahigkeiten. Diese Tatsache spiegelt sich wider in dem angelsachsis,;hen Schlagwort "non-standard date base applications", was sich vielleicht mit "nicht-konventionelle Datenbank-Anwendungen" wiedergeben lasst. Fur derartige Anwendungen werden immer haufiger neuartige DB-Systeme gefordert. Die Datenbank-Forschung griff diese Problematik schon vor einigen Jahren verstarkt auf. Das lasst sich belegen durch das Fachgesprach Datenbanken der GI -Jahrestagung 1983, aber auch durch so renommierte internationale Konferenzen wie SIGMOD '84 oder VLDB84 , bei denen sich etwa 50 % der Beitrage mit Datenbank-Problemen beschaftigten, die sich durch Anwendungen in Buro, Technik und Wissenschaft stellen. Unter diesen Umstanden hielt es der Fachausschuss 2.5 "Rechnergestutzte Informations- systeme" der Gesellschaft fur Informatik fur angebracht, eine Fachtagung eigens uber Datenbanksysteme fur die Unterstutzung von Burotatigkeiten und fur technisch-wissen- schaftliche Anwendungen auszurichten. Die erfreulich grosse Resonanz, die der Aufruf zu Tagungsbeitragen fand, hat diese Einschatzung bestatigt. Es ist den Veranstaltern ein Bedurfnis, an dieser Stelle den vielen Autoren zu danken, die durch ihre einge~ reichten Beitrage die Bedeutung der Thematik unterstrichen haben, und zwar ausdrucklich auch denen, deren Beitrage nicht im Tagungsprogramm erscheinen. In den meisten Fallen ist der Grund dafur nicht die mangelnde Qualitat, sondern der Zwang zur zeitlichen und thematischen Konzentration, der die Organisatoren vor die Qual der Wahl stellte.