Combinatorial chemistry and molecular diversity approaches to scientific and novel product R & D have exploded in the 1990s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. The second volume in this series includes contributions on methods, solid phases, purification, analysis, carbohydrates, patent strategies and tactics, diversity profiling and combinatorial series design, and finishes with a survey of chemical libraries yielding biologically active agents and a compendium of solid phase chemistry publications. Each contribution is prepared by a recognized expert resulting in a high quality account of the recent advances in the field.

Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date.

In this collection, both individually and collectively, the authors explore the gendering of women's experiences in academia through the lens of narratives of lived experience. This is a cogent theme throughout the book, reflecting on women's experiences as intersectional-always raced, classed, gendered, nuanced and complex. Jointly, the chapters provide important insights into individual and collective contemporary women's experiences in academia from international perspectives, such as gender equity, barriers to success, and achievement. This comprehensive volume provides a reference point for all women and their colleagues working in universities and colleges across the world.

Giddy up! Your guide to horseback riding is here! There's nothing quite like the sound of a horse's gallop. Add to that the sight of its mane catching wind as its powerhouse body criss-crosses the boundary of strength and graceful agility. They are majestic creatures to behold--and if you've caught the equine bug, Horseback Riding For Dummies is all you need to get saddled up and started on your journey to riding into the sunset! Inside, riders at the beginner level will discover the differences between Western and English riding styles, get the knowledge to select the best stable and instructor, and so much more! Choose the riding discipline that best suits your interests Find a qualified riding instructor Learn how to enter the competitive riding world Fit and care for the saddle, bridle, and other equipment Once you've fallen for one of these beautiful animals, it's hard to hold your horses--and this guide is here to give you the skills and know-how to take that excitement to the ring!

Every single person in America was touched by the events of World War II. Sixteen million Americans served their country in every corner of the globe. This is the story of a group of men who went off to war. They are all from one town, Stamford, CT, but their stories are universal. Author Tony Pavia has interviewed veterans from Stamford, listening to their personal stories as well as stories from those loved ones whom the veterans left behind. One of the most comprehensive oral histories of its kind, this book chronicles every major theater, battle and branch of service in the words of those who lived it.

Every single person in America was touched by the events of World War II. Sixteen million Americans served their country in every corner of the globe. This is the story of a group of men who went off to war. They are all from one town, Stamford, CT, but their stories are universal. Author Tony Pavia has interviewed veterans from Stamford, listening to their personal stories as well as stories from those loved ones whom the veterans left behind. One of the most comprehensive oral histories of its kind, this book chronicles every major theater, battle and branch of service in the words of those who lived it.

Updated for today's beginning horse enthusiasts! If you're just getting into the world of horses, there's a lot to learn! Horses For Dummies gets beginning-level riders and aspiring first-time horse owners up to speed on all things equine! From selecting the right horse for you to feeding, grooming, and handling a horse, this book covers it all! Featuring updates on breeds, boarding, nutrition, equipment, training, and riding--as well as new information on various equine conditions--this resource shows you how to keep your horse happy and take your riding skills to the next level. Features updated safety information Includes more riding disciplines Offers tips for better nutrition for your horse Provides grooming and training recommendations If you're crazy about horses, this hands-on guide is all you need to giddy up and go!

Student engagement is fundamental to learning, yet it also constitutes a major and long-standing challenge to educators around the world. This book provides an evidence-based theorisation of features associated with schooling engagement, along with targeted strategies that underpin a continuum of pedagogical, curricular and social support during the years of young adolescent schooling. Anchored by the Young Adolescent Engagement in Learning Model, a multi-layered model which incorporates a continuum of behavioural, emotional and cognitive dimensions of engagement, the authors provide a framework to help support the engagement of young adolescents. Seamlessly integrating theory and practice, this book explores the importance of avoiding educational disengagement, particularly from those who are most vulnerable due to a range of personal factors. This volume will be of interest and value to students and scholars of educational young adolescent engagement and retention, as well as those working with young people.

Featuring new experiments, a new essay, and new coverage of nanotechnology, this organic chemistry laboratory textbook offers a comprehensive treatment of laboratory techniques including small scale and some microscale methods that use standard-scale ("macroscale") glassware and equipment. The book is organized based on essays and topics of current interest and covers a large number of traditional organic reactions and syntheses, as well as experiments with a biological or health science focus. Seven introductory technique-based experiments, thirteen project-based experiments, and sections on green chemistry and biofuels spark students' interest and engage them in the learning process. Instructors may choose to offer Cengage Learning's optional Premium Website, which contains videos on basic organic laboratory techniques.

Hundreds of Americans from the town of Stamford, Connecticut, fought in the Vietnam War. Of those, 29 did not return. These men and women came from all corners of the town. They were white and black, poor and wealthy. Some had not finished high school; others had graduate degrees. They served as grunts and helicopter pilots, battlefield surgeons and nurses, combat engineers and mine sweepers. Greeted with indifference and sometimes hostility upon their return home, they learned to suppress their memories in a nation fraught with political, economic and racial tensions. Now in their late 60s and 70s, these veterans have begun to tell their stories, which have been collected and recorded in this book.

Want to know the best ways to care for your horse? "Horse Health and Nutrition For Dummies" gives you up-to-the-minute guidance on keeping horses healthy at all stages of life. It provides the latest information on equine nutrition and healthcare, explaining how your horse's body functions and how to keep it in good working order.

Packed with practical advice on equine first aid and alternative therapies, this completely practical, plain-English guide explains exactly what to feed your four-legged "hayburner" and how much. You'll find out what kind of preventive care is vital to keeping your horse in good physical shape and how to recognize signs of illness when things go wrong. You'll get the low-down on the diseases and conditions most likely to plague the domestic horse and find help in deciding whether to treat problems yourself or call the vet. Discover how to: Manage your horse's dietHouse your horse safely and comfortablyTend to the daily details of horse careExamine coat, eyes, hooves and manureIdentify, control, and prevent equine diseasesUnderstand links between horse behavior and healthPractice good horse nutritionGrow your own horse foodCover horse-health-care costsBreed your horseCare for pregnant mares and newborns

A healthy horse is a happy horse. Keep your horse fit with a little help from "Horse Health and Nutrition For Dummies, " and you'll be happy too

Combinatorial chemistry and molecular diversity approaches to scientific and novel product R & D have exploded in the 1990s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. The second volume in this series includes contributions on methods, solid phases, purification, analysis, carbohydrates, patent strategies and tactics, diversity profiling and combinatorial series design, and finishes with a survey of chemical libraries yielding biologically active agents and a compendium of solid phase chemistry publications. Each contribution is prepared by a recognized expert resulting in a high quality account of the recent advances in the field.

The authoritative information and advice you need, illustrated throughout with full-color photographs.
Hermit crabs are social creatures, so most owners have several. They're easy to care for and fascinating to watch as they grow, molt, climb, dig, burrow, and crawl. They ""adopt"" shells that they carry on their back like a mobile home With colorful photos and helpful tips, this practical guide covers everything you need to know to get started, including:
* Choosing your hermit crabs
* Setting up an interesting crabitat with a warm, humid environment
* Essential equipment and supplies
* Handling, feeding, and misting your hermit crabs
* Providing extra shells so your critters can change shell ""housing"" as they grow

Discover intriguing ways to have fun with hermit crabs. They're truly low cost, low maintenance, captivating pets.

Experience the sheer joy of being one with your horse and one with nature.

When you're riding the trails with your horse, you enjoy a refreshing feeling of freedom, the exhilaration of exploration, and an invigorating escape from the demands of the day. You're in control--as long as you can control the 1,000-pound creature you're riding. Trail Riding: A Complete Guide takes you from the basics to more advanced trail riding skills with information on: How to choose a horse, including basics on conformation Finding the best trail-riding lessons, tack, and equipment Feeding, care, grooming, health care, and stable management Conditioning--for the horse and yourself Trailering to trails Advanced trail riding, including information on camping with your horse, how competitive trail riding is judged, and racing on the trail Tips on how to find the best trails, both locally and around the country

This book helps you develop the knowledge and skills that will give you a leg up every time you climb in the saddle. You and your horse will become the perfect pair for relaxing yet energizing adventures off the beaten path.

The authoritative information and advice you need, illustrated throughout with full-color photographs--now revised and redesigned to be even more reader-friendly!
* An illustrated look at colors and breeds
* The story of how guinea pigs were domesticated
* Advice on selecting a guinea pig
* Pointers on feeding, grooming, and health
* Tips on understanding guinea pig behavior
* Fun activities to enjoy with your guinea pig

The authoritative information and advice you need, illustrated throughout with full-color photographs--now revised and redesigned to be even more reader-friendly
* An illustrated look at colors and breeds
* The story of how guinea pigs were domesticated
* Advice on selecting a guinea pig
* Pointers on feeding, grooming, and health
* Tips on understanding guinea pig behavior
* Fun activities to enjoy with your guinea pig

Why are Jack Russell Terriers so popular?
How much does it cost to keep a JRT?
What kind of behavioral problems do JRTs have?
That little Jack Russell Terrier puppy is so adorable-but is he the right dog for you? Many prospective dog owners don't ask the questions they should when they're deciding to bring a new puppy home. Now, the What About? series is here to help you understand the real-life implications of your decision, saving you time, money, and potential heartache-and protecting you and the dog from the consequences of an inappropriate choice.
Drawing upon the expertise of Jack Russell Terrier breeders, owners, rescue organizations, veterinarians, and trainers, What About Jack Russell Terriers? provides honest, reliable advice on what it's really like to own a JRT-no punches pulled. In a friendly, easy-to-follow Q&A format, author Audrey Pavia offers solid, proven guidance on everything you need to know about raising a JRT, including:
Breed characteristics ? Behavior ? Costs of ownership ? Development in all life stages ? Diet ? Exercise requirements ? Genetics and why it's important ? Health and general care ? Temperament ? Training requirements ? Working with behaviorists, trainers, and veterinarians ? And more
Don't be taken by surprise. Get the answers you need now-before you get that Jack Russell Terrier puppy-and make a smart, informed decision.

Facts and tips on a boisterous, high-energy breed

Sure, the Jack Russell dog Eddie on Frasier looks lovable on TV, but would he fit into any other family just as well? What About Jack Russell Terriers? presents realistic, honest answers to important questions concerning this breed’s behavior, health and genetics, diet, development, and much more. Before bringing that cute puppy home, this guide explains how much Jack Russells cost and how much exercise and training they require, reveals how the breed behaves with children, and helps readers determine a prospective puppy’s temperament. Providing easy lookup of topics and information expressed in everyday language (and avoiding dog jargon), this book answers the most frequently asked questions of owners, veterinarians, breeders, and trainers about these feisty, energetic dogs.

Audrey Pavia (Santa Ana, CA) is a former managing editor of Dog Fancy and a former senior editor of the AKC Gazette. She has written hundreds of articles about dogs, horses, and other companion animals, and several books.

Gain an understanding of the latest advances in spectroscopy with INTRODUCTION TO SPECTROSCOPY.This proven book provides a systematic introduction to spectra and basic theoretical concepts in spectroscopic methods and includes up-to-date spectra; a modern presentation of one-dimensional nuclear magnetic resonance (NMR) spectroscopy; an introduction to biological molecules in mass spectrometry; and coverage of modern techniques alongside DEPT, COSY, and HECTOR.

Covid-19: Biomedical Perspectives, Volume 50 in the Methods in Microbiology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Individual chapters in this new release include Sensitive methods for detection of SARS-CoV-2 RNA, Treatment of COVID-19 using Chinese herbal medicine, Understanding how SARS-CoV-2 is evolving and its impact on COVID-19 animal models and vaccine evaluation, Methods in machine learning to identify COVID-19 literature, COVID-19 seasonal behavior and the mutational landscape of the SARS-CoV-2 virus, CRISPR use in Diagnosis and Therapy for COVID-19, and much more.

Immunological Methods in Microbiology, Volume 47 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Immunological Techniques in the Clinical laboratory, Immunologic Diagnosis of HIV and Opportunistic Infections, Combining Antigen Detection and Serology for the Diagnosis of Selected Infectious Diseases, Immunologic Detection of Lyme Disease and Related Borrelioses, Immunodetection of Bacteria Causing Brucellosis, Immunological Diagnostic Techniques Used to Identify and Type Pasteurella, Immunological Tests for Diarrhea caused by Diarrheagenic Escherichia coli Targeting Their Main Virulence Factors, and much more.

How will automated vehicles change our lives? Where are the opportunities and challenges? Future streets require planning today. This timely book envisions ways in which changes to urban mobility and technology will transform city streetscapes and, importantly, how cities can prepare. It is a reflection on the relationship between new technologies and urbanism, as well as an agile urban design manual with pictures illustrating potential spatial arrangements enabled by the new technologies. Two case studies in the central urban cores of London and Los Angeles will be presented to show how neighborhoods can be redesigned for the better and how to apply good urban design principles across towns and cities worldwide.