Summer of Caprice, a captivating comic novel first published in 1926, is a classic of Czech literature, yet it is little known elsewhere. Commonly considered untranslatable due to the complexities of the text, which is characterized by a playful narrative and an exceptional mastery of language, and its profound cultural context, it is rendered here in English that beautifully captures Vladislav Vancura's experimental style or, as the author himself called it, his "poetism in prose." Mixing the archaic with the innovative, raw colloquialisms with biblical quotations, Summer of Caprice opens an uproarious window onto the Czech spirit, humor, and way of life.

This book discusses current challenges related to teaching geography, mainly at the secondary school and higher education level. Focusing on a range of current topics, different methods, techniques, materials, applications, and approaches to geography education with a regional Central European perspective, the book makes an original contribution to the field. Most of the chapters aims at the practical development of the themes such as geography curriculum (Part I), global education, inquiry-based education, project-based learning, case studies, powerful teaching (Part II), using of information and communication technologies (Part III) in geography teaching. The final part (Part IV) covers some geopolitical, and socio-geographical aspects of the aforementioned Central European former communist countries from the point of view how to teach them with various methods. Therefore, the book can appeal to many geography or science students, researchers and educators studying geography education around the world.

This book discusses current challenges related to teaching geography, mainly at the secondary school and higher education level. Focusing on a range of current topics, different methods, techniques, materials, applications, and approaches to geography education with a regional Central European perspective, the book makes an original contribution to the field. Most of the chapters aims at the practical development of the themes such as geography curriculum (Part I), global education, inquiry-based education, project-based learning, case studies, powerful teaching (Part II), using of information and communication technologies (Part III) in geography teaching. The final part (Part IV) covers some geopolitical, and socio-geographical aspects of the aforementioned Central European former communist countries from the point of view how to teach them with various methods. Therefore, the book can appeal to many geography or science students, researchers and educators studying geography education around the world.

Through many recent remarkable developments, perhaps the most significant advancements in the study of transcriptional regulation are the development of genome-wide approaches for measuring gene expression, exemplified by gene chips (chip), and chromatin immunoprecipitation assays (ChIP) for measuring in vivo protein-DNA interactions at any genomic loci. Transcriptional Regulation: Methods and Protocols takes this progress and builds upon it with a collection of key protocols used in expert laboratories around the world. Divided into four convenient sections, this detailed volume explores promoter elements, transcription factors, and preinitiation complex (PIC) assembly, chromatin structure, chromatin modifying complexes, and RNA synthesis and regulation. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls. Comprehensive and accessible, Transcriptional Regulation: Methods and Protocols equally serves senior researchers and scientists experienced in transcriptional regulation as well as graduate students and scientists who wish to study transcriptional regulation for the first time.

As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.

Through many recent remarkable developments, perhaps the most significant advancements in the study of transcriptional regulation are the development of genome-wide approaches for measuring gene expression, exemplified by gene chips (chip), and chromatin immunoprecipitation assays (ChIP) for measuring "in vivo" protein-DNA interactions at any genomic loci. "Transcriptional Regulation: Methods and Protocols" takes this progress and builds upon it with a collection of key protocols used in expert laboratories around the world. Divided into four convenient sections, this detailed volume explores promoter elements, transcription factors, and preinitiation complex (PIC) assembly, chromatin structure, chromatin modifying complexes, and RNA synthesis and regulation. Written in the highly successful "Methods in Molecular Biology " series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and vital tips on troubleshooting and avoiding known pitfalls.

Comprehensive and accessible, "Transcriptional Regulation: Methods and Protocols" equally serves senior researchers and scientists experienced in transcriptional regulation as well as graduate students and scientists who wish to study transcriptional regulation for the first time."

A Chronicle style tale of a man of legend in his world. Follow his past, present and future stories in this semi blog format. Wherein not only L.J. Stevans posts but others from his life posts about and sometimes to him. His beginnings appear humble but his life turns on a dime at the age of 14 when he witnesses his Mothers murder. Follow his journey from boy to Folk Hero to a man just trying to figure out the strange circumstances that surround his life. Never did he imagine that some day the fate of a generation would rest on his shoulders I never asked to be a hero. Nor did I ask to be born this way. However, I can't change the road I am walking now. Some paths must be taken to mold you into the person you were meant to be. I know that now. Still, it does not define me, or guide my actions. Normal was never an option. I am L.J. Stevans and I am incapable of telling a lie.