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In recent years the inferior olive and its projection to the
cerebellum have attracted considerable interest. Numerous
experimental anatomic and electrophysiologic studies have been
undertaken, and much new information has been brought forward. Many
apparently discordant observations have been reported however, and
on many points the data obtained by the use of different methbds
and approaches appear to be diffi cult to reconcile. Much of the
interest in the olivocerebellar projection concerns the
topographical localization within the projection. Particularly as a
result of research in recent years the pattern of localization has
turned out to be far more complex than previously be lieved. It was
found useful, therefore, to attempt a review of the subject in the
hope that a critical analysis of available observations might make
it possible to obtain an integrated picture of the olivocerebellar
projection and perhaps fmd some basic principles in the
organization of this fiber system. As will be seen, our attempt has
been only partly successful. There are still riddles that remain to
be solved. In the present review attention will be focused on
problems related to the locali zation within the olivocerebellar
projection, particularly its anatomic aspects. An extensive review
of the physiology of the inferior olive has been published recently
by Armstrong (1974), who considers some anatomicophysiologic
correlations as well. Physiologic fmdings will be referred to here
mainly in relation to our main theme."
Unique among neuroanatomical texts ... This is no dry compilation
of facts but an attention-rivetting discussion of neurological
organization.' Annals of Internal Medicine on the 2nd edition.
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