Research and industrial developments in the theoretical and practical aspects of safety and security engineering are the focus of this volume. This field, due to its special nature, is an interdisciplinary area of research and application that brings together, in a systematic way, many disciplines of engineering from the traditional to the most technologically advanced. The included papers, which were originally presented at the 13th Conference on Risk Analysis, Hazard Mitigation and Safety and Security Engineering, cover areas such as crisis management, security engineering, natural disasters and emergencies, terrorism, IT security, man-made hazards, pandemics, transportation security, protection and mitigation issues, among others. Also covered are various aspects of risk management and hazard mitigation, associated with both natural and anthropogenic hazards. Current events help to emphasise the importance of the analysis and management of risk to planners and researchers around the world. Natural hazards such as floods, earthquakes, landslides, fires, epidemics, transportation, climate change, fake news and others have always affected human societies. The more recent emergence of the importance of man-made hazards is a consequence of the rapid technological advances made in the last few centuries. The interaction of natural and anthropogenic risks adds to the complexity of the problems.