This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more than 60 chapters experts present state-of-the-art reviews of this fascinating field, the topics ranging from molecular biology to clinical applications. Part I covers the multiplicity of opioid receptors, the chemistry of opiates and opioid peptides as well as the neurophysiology of opioids. Part II reviews a broad spectrum of physiological and behavioral functions and pharmacological actions of opioids, together with their neuroendocrinology, opioid tolerance and dependence, concluding with pathophysiological aspects and clinical use.

Hundreds of rare illustrations depict wide range of design alternatives for prospective homeowners and other customers of the late 19th century. While the collection includes elevations and floor plans for a variety of handsome, private residences and commercial structures, the emphasis is on architectural details -- from dormer windows to balconies.

This treasury of floor plans, elevations, and details of suburban residences is an endless source of inspiration for artists, architects, and historians alike. Eighty-one detailed illustrations capture the elaborate beauty of Victorian-era cornices, staircases, gables, verandas, doors, dormers, and more. A bonus section offers construction guidelines for masons, bricklayers, and carpenters.

Originally published in 1878, this now-rare collection of designs by a leading 19th-century architectural firm supplies views of a remarkable variety of modestly priced structures: suburban houses, villas, seaside and campground cottages, and many other buildings. The designs are presented in handsome drawings of perspective views and elevations, some of which include floor plans. Suggestions for interior decor include sideboards, newel posts, and entire suites of furniture. The result is an authentic treasury of Victorian design, sure to intrigue historians of architecture, home restorers, preservationists, and anyone who delights in the felicities of the American Victorian style. Unabridged reprint of the 1878 edition. Index. 98 b/w illustrations.