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High fluorides ingestion through drinking water affects the body
system of human being. No treatment was successful in the children
with fluorosis. This study reports successful treatment of
fluorosis in children and possible preventive measures. Double
blind cross sectional clinical study was conducted on 200 children
consuming water containing 2.4, 4.6, 5.6 and 13.5 mg/l of fluoride
of various age groups. A note was made for clinical, radiological
and dental fluorosis. Biochemical estimations were made for serum
calcium, serum and urinary fluoride and serum parathyroid hormone.
It was observed that high Fluoride ingestion causes increased
parathyroid hormone secretion, which is responsible for maintaining
serum calcium levels and leading to manifestations of fluorosis.
The supplementation of a therapeutic regime of Calcium, Vitamin C
and Vitamin D in these children reported reversal of fluorosis,
indicating that this therapy can be employed successfully in
children suffering from fluorosis. For prevention, Intake of
fluoride can be reduced by the use of simple defluoridation
technique, reducing intake of fluoride rich items and use of food
rich in calcium, Vitamin C and protein.
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