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In the first edition of The Enzymes of Biological Membranes,
published in four volumes in 1976, we collected the mass of widely
scattered information on membrane-linked enzymes and metabolic
processes up to about 1975. This was a period of transition from
the romantic phase of membrane biochemistry, preoccupied with
conceptual developments and the general properties of membranes, to
an era of mounting interest in the specific properties of
membrane-linked enzymes analyzed from the viewpoints of modem
enzymology. The level of sophistication in various areas of
membrane research varied widely; the structures of cytochrome c and
cytochrome b5 were known to atomic detail, while the majority of
membrane-linked enzymes had not even been isolated. In the
intervening eight years our knowledge of membrane-linked enzymes ex
panded beyond the wildest expectations. The purpose of the second
edition of The Enzymes of Biological Membranes is to record these
developments. The first volume describes the physical and chemical
techniques used in the analysis of the structure and dynamics of
biological membranes. In the second volume the enzymes and met
abolic systems that participate in the biosynthesis of cell and
membrane components are discussed. The third and fourth volumes
review recent developments in active transport, oxidative
phosphorylation and photosynthesis."
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