Many advances have been made in the field of thermoregulation in the past few years. These include our understanding of Fever, which is now considered not simply a rise in deep body temperature foHowing infection, but just one aspect, though perhaps the most easily measured, of the Acute Phase of the Immune Response. Classification and identification of the Cytokines and the availability of recombinant material has greatly aided this research. Similarly, our understanding of the Hypothalamo-Pituitary Adrenal Axis has altered our way of thinking about temperature regulation. Of importance are the problems associated with adverse climatic conditions and survival, and the problems encountered by the neonate and the hibernator. At the biochemical level, our knowledge of the control of heat production and the role of brown adipose tissue is rapidly advancing. All these issues and many others were discussed at a Symposium 'Thermal Physiology 1993' held in Aberdeen, Scotland in August 1993 under the auspices of the Thermal Physiology Commission of the International Union of Physiological Sciences. Six main aspects of the subject of temperature regulation are included in this book, namely, Fever (including the Acute Phase of the Immune Response and Thermoregulatory Peptides), Neurophysiology of Thermoregulation, Neonatal Thermoregulation, Mechanisms of Heat Production, Ecological and Behavioural Thermoregulation, and Emerging Themes in Thermoregulation.

This review volume is intended to survey the field of quantum fluctuational phenomena induced by material bodies, which is commonly encompassed under the name of Casimir physics. H B G Casimir first discovered that zero-point fluctuations in the electromagnetic field caused an attractive force between closely separated metallic plates. Now - 75 years later - the field is burgeoning, with numerous experimental verifications and applications to practical devices starting to emerge.In this book, new ideas about Casimir physics are brought to bear on such diverse subjects as cosmology, where the Casimir energy may explain the dark energy that causes the cosmic repulsion, and nonstatic regimes, such as Casimir or quantum friction. Unsolved problems, including divergences in Casimir self-energies, the meaning of local energy densities in inhomogeneous backgrounds, and discrepancies between theory and experiment, are treated in some detail. It is hoped that this collection of papers will serve as an introduction to the field for newcomers to the subject, and that it will inspire a new burst of research into the nature of the quantum vacuum.

Julian Schwinger was already the world's leading nuclear theorist when he joined the Radiation Laboratory at MIT in 1943, at the ripe age of 25. Just 2 years earlier he had joined the faculty at Purdue, after a postdoc with OppenheimerinBerkeley, andgraduatestudyatColumbia. Anearlysemester at Wisconsin had con?rmed his penchant to work at night, so as not to have to interact with Breit and Wigner there. He was to perfect his iconoclastic 1 habits in his more than 2 years at the Rad Lab. Despite its deliberately misleading name, the Rad Lab was not involved in nuclear physics, which was imagined then by the educated public as a esoteric science without possible military application. Rather, the subject at hand was the perfection of radar, the beaming and re?ection of microwaves which had already saved Britain from the German onslaught. Here was a technology which won the war, rather than one that prematurely ended it, at a still incalculable cost. It was partly for that reason that Schwinger joined this e?ort, rather than what might have appeared to be the more natural project for his awesome talents, the development of nuclear weapons at Los Alamos. He had got a bit of a taste of that at the "Metallurgical Laboratory" in Chicago, and did not much like it. Perhaps more important for his decision to go to and stay at MIT during the war was its less regimented and isolated environment.

QFEXT is the leading international conference held every two years, highlighting progress in quantum vacuum energy phenomena, the Casimir effect, and related topics, both experimentally and theoretically.

This proceedings volume, featuring contributions from many of the key players in the field, serves as a definitive source of information on this field, which is playing an increasingly important role in nanotechnology and in understanding fundamental issues in physics such as renormalization and in the search for new physics such as fifth forces and dark energy.

Starting from the earlier notions of stationary action principles, these tutorial notes shows how Schwinger's Quantum Action Principle descended from Dirac's formulation, which independently led Feynman to his path-integral formulation of quantum mechanics. Part I brings out in more detail the connection between the two formulations, and applications are discussed. Then, the Keldysh-Schwinger time-cycle method of extracting matrix elements is described. Part II will discuss the variational formulation of quantum electrodynamics and the development of source theory.

Many advances have been made in the field of thermoregulation in the past few years. These include our understanding of Fever, which is now considered not simply a rise in deep body temperature foHowing infection, but just one aspect, though perhaps the most easily measured, of the Acute Phase of the Immune Response. Classification and identification of the Cytokines and the availability of recombinant material has greatly aided this research. Similarly, our understanding of the Hypothalamo-Pituitary Adrenal Axis has altered our way of thinking about temperature regulation. Of importance are the problems associated with adverse climatic conditions and survival, and the problems encountered by the neonate and the hibernator. At the biochemical level, our knowledge of the control of heat production and the role of brown adipose tissue is rapidly advancing. All these issues and many others were discussed at a Symposium 'Thermal Physiology 1993' held in Aberdeen, Scotland in August 1993 under the auspices of the Thermal Physiology Commission of the International Union of Physiological Sciences. Six main aspects of the subject of temperature regulation are included in this book, namely, Fever (including the Acute Phase of the Immune Response and Thermoregulatory Peptides), Neurophysiology of Thermoregulation, Neonatal Thermoregulation, Mechanisms of Heat Production, Ecological and Behavioural Thermoregulation, and Emerging Themes in Thermoregulation.

Fever has always been recognised as the major sign of infectious disease as well as being associated with other illnesses. The suggestion of publishing a volume dedicated exclusively to the subject of fever in the Handbook of Experimental Pharmacology series was one that greatly appealed to me, and I felt very honoured when I was invited to edit it. The first ideas about this volume were conceived in the latter part of 1977 and by the middle of 1978 the first authors had been approached. As is usual with such publications, by the time the first manuscripts were beginning to arrive in the late spring of 1979 there were still a few chapters for which authors had not yet been found. Finally by the end of 1981 the volume was complete. Because of the span of time over which the chapters were written, some refer to more recent work than others; however, I do not feel that this detracts from the overall contribution of all the chapters.

Julian Schwinger was already the world's leading nuclear theorist when he joined the Radiation Laboratory at MIT in 1943, at the ripe age of 25. Just 2 years earlier he had joined the faculty at Purdue, after a postdoc with OppenheimerinBerkeley, andgraduatestudyatColumbia. Anearlysemester at Wisconsin had con?rmed his penchant to work at night, so as not to have to interact with Breit and Wigner there. He was to perfect his iconoclastic 1 habits in his more than 2 years at the Rad Lab. Despite its deliberately misleading name, the Rad Lab was not involved in nuclear physics, which was imagined then by the educated public as a esoteric science without possible military application. Rather, the subject at hand was the perfection of radar, the beaming and re?ection of microwaves which had already saved Britain from the German onslaught. Here was a technology which won the war, rather than one that prematurely ended it, at a still incalculable cost. It was partly for that reason that Schwinger joined this e?ort, rather than what might have appeared to be the more natural project for his awesome talents, the development of nuclear weapons at Los Alamos. He had got a bit of a taste of that at the "Metallurgical Laboratory" in Chicago, and did not much like it. Perhaps more important for his decision to go to and stay at MIT during the war was its less regimented and isolated environment.

Julian Schwinger was already the world's leading nuclear theorist when he joined the Radiation Laboratory at MIT in 1943, at the ripe age of 25. Just 2 years earlier he had joined the faculty at Purdue, after a postdoc with OppenheimerinBerkeley,andgraduatestudyatColumbia. Anearlysemester at Wisconsin had con?rmed his penchant to work at night, so as not to have to interact with Breit and Wigner there. He was to perfect his iconoclastic 1 habits in his more than 2 years at the Rad Lab. Despite its deliberately misleading name, the Rad Lab was not involved in nuclear physics, which was imagined then by the educated public as a esoteric science without possible military application. Rather, the subject at hand was the perfection of radar, the beaming and re?ection of microwaves which had already saved Britain from the German onslaught. Here was a technology which won the war, rather than one that prematurely ended it, at a still incalculable cost. It was partly for that reason that Schwinger joined this e?ort, rather than what might have appeared to be the more natural project for his awesome talents, the development of nuclear weapons at Los Alamos. He had got a bit of a taste of that at the "Metallurgical Laboratory" in Chicago, and did not much like it. Perhaps more important for his decision to go to and stay at MIT during the war was its less regimented and isolated environment.

Only those who have an undeniable calling from God will be fit for the challenges and strains of the ministry life. But how do you test a calling and how do you proceed if you are certain its legitimacy? From the theology of being called, to selecting a seminary, to beginning life as a pastor, Michael Milton looks to the Word of God for answers and guidance, as well as drawing on his own experience as a Presbyterian minister.