The book is the definitive reference on one of the most exciting areas of life science research - stem cells and their use in repair and regeneration of different organs and tissues. The volume is rounded off by a set of chapters on basic stem cell biology and clinical applications and clinical experiences of stem cell therapy, considering cardiovascular disease, neurological diseases, liver disease and diabetes. These offer a sound and well-balanced view of successes to date and indications for future therapeutic routes. It presents the current state of knowledge in both basic science and clinical practice, and is an essential reference for scientists, students and clinicians. It was a great pleasure to work with our colleagues who graciously gave their time to bring this project to fruition. Although it would be impossible to delve into all the controversies and nuances of stem cell-based therapies, we believe readers will find this to be a detailed and fair representation of the current state of knowledge.

The book included study of the disturbances caused as a result of the gamma irradiation. The new researches directed to search in the nature for new natural products rich in antioxidants polyphenolic compounds. The willow leaves were selected to be under study. The book included studying protective effect of the aqueous extract of Willow leaves with all the active ingredients against the biochemical and the molecular disturbances occurred due to the exposure to gamma rays. The study followed the genetic abnormalities transmitted from the irradiated parents to the next generations and studying the antagonistic effect of willow extract against inheritance of these genetic disturbances in rats.