The volume LNAI 12228 constitute the refereed proceedings of the 21th Annual Conference "Towards Autonomous Robotics," TAROS 20120, held in Nottingham, UK, in September 2020.*The 30 full papers and 11 short papers presented were carefully reviewed and selected from 63 submissions. The papers present and discuss significant findings and advances in autonomous robotics research and applications. They are organized in the following topical sections: soft and compliant robots; mobile robots; learning, mapping and planning; human-robot interaction; and robotic systems and applications. * The conference was held virtually due to the COVID-19 pandemic.