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After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.
Climate change is changing the context of spatial planning and shaping its priorities. It has strengthened its environmental dimension and has become a new rationale for coordinating actions and integrating different policy priorities. This book sets out the economic, social and environmental challenges that climate change raises for urban and regional planners and explores current and potential responses. These are set within the context of recent research and scholarly works on the role of spatial planning in combating climate change. Addressing both mitigation measures for reducing greenhouse gas emissions and adaptation to the effects of climate change, the book provides an overview of emerging practice, with analysis of the drivers of policy change and practical implementation of measures. It scopes planning issues and opportunities at different spatial scales, drawing on both the UK and international experiences and highlighting the need to link global and local responses to shared risks and opportunities.
Climate change is changing the context of spatial planning and shaping its priorities. It has strengthened its environmental dimension and has become a new rationale for coordinating actions and integrating different policy priorities. This book sets out the economic, social and environmental challenges that climate change raises for urban and regional planners and explores current and potential responses. These are set within the context of recent research and scholarly works on the role of spatial planning in combating climate change. Addressing both mitigation measures for reducing greenhouse gas emissions and adaptation to the effects of climate change, the book provides an overview of emerging practice, with analysis of the drivers of policy change and practical implementation of measures. It scopes planning issues and opportunities at different spatial scales, drawing on both the UK and international experiences and highlighting the need to link global and local responses to shared risks and opportunities.
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