The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.

Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.

Disaster Victim Identification: A Manager’s Guide to Policy and Procedure’s guiding thesis explains why disaster victim identification (DVI) must be fundamentally integrated—at the outset—into general disaster planning and operations procedures. By doing so, it allows for pre-event assessment of any risks and vulnerabilities, in coordination with planning and response agencies, so that the on-site response isn’t the first time they have communicated and worked together. The book outlines the importance of exercising, interagency memoranda of understanding (MOU), and coordination in advance to provide the best, most effective response that optimally serves both the victims and the community. DVI requires a multi-disciplinary approach and, as such, plans should take into consideration and account for possible integration of outside assistance into the general work plan and flow. By doing this, practical action and measures—sometimes coordinated impromptu depending on the nature and scale of a disaster—can be undertaken both quickly and seamlessly. Coverage outlines the overall DVI process, its various methodologies, and how it serves as an integral part of overall disaster response. Disaster Victim Identification brings together the expertise of two professionals with longstanding, extensive first-hand experience in the field. This includes working at, as well as supervising coordination of, DVI response to such scenes. The book will be a welcome addition to professionals by examining what works, what doesn’t, and how to maintain best practices while avoiding common mistakes.

Disaster Victim Identification: A Manager’s Guide to Policy and Procedure’s guiding thesis explains why disaster victim identification (DVI) must be fundamentally integrated—at the outset—into general disaster planning and operations procedures. By doing so, it allows for pre-event assessment of any risks and vulnerabilities, in coordination with planning and response agencies, so that the on-site response isn’t the first time they have communicated and worked together. The book outlines the importance of exercising, interagency memoranda of understanding (MOU), and coordination in advance to provide the best, most effective response that optimally serves both the victims and the community. DVI requires a multi-disciplinary approach and, as such, plans should take into consideration and account for possible integration of outside assistance into the general work plan and flow. By doing this, practical action and measures—sometimes coordinated impromptu depending on the nature and scale of a disaster—can be undertaken both quickly and seamlessly. Coverage outlines the overall DVI process, its various methodologies, and how it serves as an integral part of overall disaster response. Disaster Victim Identification brings together the expertise of two professionals with longstanding, extensive first-hand experience in the field. This includes working at, as well as supervising coordination of, DVI response to such scenes. The book will be a welcome addition to professionals by examining what works, what doesn’t, and how to maintain best practices while avoiding common mistakes.

Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.

Polysaccharides are natural, renewable materials that are biodegradable and biocompatible, making them ideal subjects for biomedical applications. This book focusses on the main polysaccharides, including but not limited to chitosan, cellulose, alginate, dextran, guar gum, gellan gum, pullulan, locust bean gum, pectin, xanthan gum, starch, hyaluronan and carrageenan, and their applications in drug delivery, imaging and tissue engineering. With contributions from around the world, the editors have pulled together a tightly curated set of chapters which showcase how polysaccharide-based materials are employed in a range of biomedical systems. The end result is a book in which the reader can gain a sound overview of this important class of material for biomedical applications, without scouring journal articles. Those working in materials science, biomedical and chemical engineering, and pharmaceutical technologies will find this a must-have reference.

With the need to combat emerging infectious diseases, research around antimicrobial biomaterials and their applications is booming. This book provides the field with a much-needed fundamental overview of the science, addressing the chemistry of a broad range of biomaterial types, and their applications in the biomedical industry. Materials covered include polymers, from those with inherent antimicrobial activity to those that release antimicrobial agents, antimicrobial ceramics and inorganic compounds, such as metal based antimicrobial additives, and the developing field of biomimetic materials, are discussed. Surfaces, coatings and adhesives are covered, whilst the applications of these antimicrobial materials in biomedical applications, from catheters to orthopaedics, dentistry to ophthalmology, are explored. Edited by international leaders and with contributions from the best in the field, this book is the go-to resource for graduates and researchers in biomaterials science, biomedical engineering, chemical engineering, and materials and polymer chemistry.