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The goal of this work is summarize the contribution that
insertional mutagenesis has made to our understanding of cancer. A
variety of insertional mutagens are presented that have been used
to study a variety of tumor types in several model organisms. In
addition, the impact of insertional mutagenesis in several gene
therapy trials is discussed along with strategies to avoid such
complications in future clinical trials.
The goal of this work is summarize the contribution that
insertional mutagenesis has made to our understanding of cancer. A
variety of insertional mutagens are presented that have been used
to study a variety of tumor types in several model organisms. In
addition, the impact of insertional mutagenesis in several gene
therapy trials is discussed along with strategies to avoid such
complications in future clinical trials.
This is a reproduction of a book published before 1923. This book
may have occasional imperfections such as missing or blurred pages,
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original artifact, or were introduced by the scanning process. We
believe this work is culturally important, and despite the
imperfections, have elected to bring it back into print as part of
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the preservation process, and hope you enjoy this valuable book.
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