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A cell is a membrane bound structure containing biomolecules, such
as nucleic acids, proteins, and polysaccharides. The Endoplasmic
Reticulum is organized into a netlike labyrinth of branching
tubules and flattened sacs extending throughout the cytosol.The ER
has a central role in lipid and protein biosynthesis.The ER
membrane makes a major contribution to mitochondrial and
peroxisomal membranes by producing most of their lipids. The
endoplasmic reticulum (ER) has many different functions. These
include the translocation of proteins (such as secretory proteins)
across the ER membrane; the integration of proteins into the
membrane; the folding and modification of proteins in the ER lumen;
the synthesis of phospholipids and steroids on the cytosolic side
of the ER membrane; and the storage of calcium ions in the ER lumen
and their regulated release into the cytosol.
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