This proceedings volume gathers selected, peer-reviewed papers presented at the 41st International Conference on Infinite Dimensional Analysis, Quantum Probability and Related Topics (QP41) that was virtually held at the United Arab Emirates University (UAEU) in Al Ain, Abu Dhabi, from March 28th to April 1st, 2021. The works cover recent developments in quantum probability and infinite dimensional analysis, with a special focus on applications to mathematical physics and quantum information theory. Covered topics include white noise theory, quantum field theory, quantum Markov processes, free probability, interacting Fock spaces, and more. By emphasizing the interconnection and interdependence of such research topics and their real-life applications, this reputed conference has set itself as a distinguished forum to communicate and discuss new findings in truly relevant aspects of theoretical and applied mathematics, notably in the field of mathematical physics, as well as an event of choice for the promotion of mathematical applications that address the most relevant problems found in industry. That makes this volume a suitable reading not only for researchers and graduate students with an interest in the field but for practitioners as well.