Today's health care systems need doctors and consultants to act as leaders, within the multi-disciplinary team, in addition to carrying out their clinical role. This book identifies the key elements of successful leadership through 'medically led' service development and systems transformation and shows how this benefits patient care, particularly when patients become partners in the process. The authors provide a conceptual framework of medical leadership and a set of scientific methods and tools that make a significant contribution to advancing quality and transforming services in healthcare. On top of this, they present analytical tools which medical professionals can use to support their own improvement or system transformation strategy, including ways of measuring improvement and the returns on investment of medical leadership. Woven throughout the book are real-life case studies from medical leaders across the world, providing students with valuable practical insights. Chapter summaries and reflections are provided to support learning. Medical Leadership will be essential reading for students on medical and clinical leadership courses internationally as well as for all practising doctors, consultants and General Practitioners.

Today's health care systems need doctors and consultants to act as leaders, within the multi-disciplinary team, in addition to carrying out their clinical role. This book identifies the key elements of successful leadership through 'medically led' service development and systems transformation and shows how this benefits patient care, particularly when patients become partners in the process. The authors provide a conceptual framework of medical leadership and a set of scientific methods and tools that make a significant contribution to advancing quality and transforming services in healthcare. On top of this, they present analytical tools which medical professionals can use to support their own improvement or system transformation strategy, including ways of measuring improvement and the returns on investment of medical leadership. Woven throughout the book are real-life case studies from medical leaders across the world, providing students with valuable practical insights. Chapter summaries and reflections are provided to support learning. Medical Leadership will be essential reading for students on medical and clinical leadership courses internationally as well as for all practising doctors, consultants and General Practitioners.

In this PhD thesis, the work is organised into separate articles that have been published. In the first part of the thesis, the electrocatalytic properties of o-aminophenol films grafted on glassy carbon surfaces have been employed for the electrochemical evaluation of hydrazine, NADH and ascorbic acid (AA). AA system was explored for clinical and food applications such as the determination of uric acid in presence of AA, and the detection of AA in real samples of fruits and vegetables using disposable screen printed electrodes. In the second part of the thesis, different surface engineering strategies of antibody immobilization for immunosensor construction using a linker (bipodal carboxylic acid terminated thiols) or via direct attachment of the SATA modified full length antibody, and their F(ab) fragments onto Au surface using a strategy of self assembly were evaluated and compared. The developed immunosensors were then applied to the detection of gliadin in commercial gluten-free and gluten-containing food products. An alternative strategy explored was the direct anchoring of the antibody with or without a linker via the electrochemical reduction of their diazonium cations.