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Biologically functional ceramic materials have been known about for
several decades, like phosphate cements and gypsum, and they are
within the zeroth generation. Modern and artificially synthesized
bioceramics include amorphous materials in the Bioglass (R) family
that were developed in the early 1970's and derivative glass
ceramics such as Bioverit (R) and Cerabone A-W (R) that came in
1980's. They are from the 2nd generation of materials, and mostly
applicable to bone replacement or bone defect fillers. Since the
late 1990's, newer technologies have been introduced to the
biologically functional material fields; they are the syntheses of
organic-inorganic hybrids of micro- and macroscopic scales as well
as nano-scales, organic fragment-covered ceramic particles of
varied sizes, with light-controlling abilities to modify the
frequency of light, in addition synthesis of high strength and
high-tribological durability that had not been available before.
With the advent of additive manufacturing technology employing
lasers, electron beams, and printers, clinical materials of
complicated porous structures are now easily prepared. These
materials are of the 3rd generation. This book will cover almost
all kinds of such 3rd generation ceramic and ceramic-related
biomaterials. This book conveys the current state-of-the-art on the
science and technology of bioceramics, from nano-size dots or
particles to macro-scale architectures, of a wide range of
constitutions including quantum dots with peptide fragments,
meso-scale therapeutic particles designed to involve drugs or
genes, mesoporous organic-inorganic hybrids, nano-structured oxide
layers on metals and alloys.
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