Norepinephrine is a chemical neurotransmitter. Drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects. Noradrenergic drugs have been proven effective for depression and ADHD, and new disease indications are being identified. A team of experts provides the reader with a thorough understanding of the anatomy, physiology, molecular biology, pharmacology and therapeutics of norepinephrine in the brain, including an extensive review of the role of norepinephrine in brain diseases. The book is divided into four sections: the basic biology of norepinephrine; the role that norepinephrine plays in behavior; evidence of norepinephrine's role in CNS diseases, and the pharmacology and therapeutics of noradrenergic drugs in the treatment of psychiatric and neurological disorders.

In The Craft of Piano Playing, master pianist Alan Fraser offers readers an original and comprehensive approach to piano technique, offering over 100 illustrations and a series of unique exercises to guide the reader. Drawing on his many years as a performer and teacher, his long-standing collaborations with pedagogue Phil Cohen and virtuoso Kemal Gekich, and his professional training in the Feldenkrais Method, Fraser introduces his truly innovative piano technique by * Teaching how to move your hands with greater sensitivity, power, and accuracy, and honing the skeletal alignments to help you access your innate, structural potency; * Linking your physical technique to musical expression, creating an "absolutely natural way of moving at the piano that is powerful, flexible, and musical" (Piano News, Germany); and * Keeping your hands healthy while avoiding the threats of tendonitis, carpal tunnel syndrome, focal dystonia, and RSI. This revised second edition joins the DVD of the same name, his study guide, and his latest book, Honing the Pianistic Self-Image, in Alan Fraser's growing line of piano pedagogical materials. This edition includes new chapters, such as "Arm Rhythm" and "The Body's Support of Natural Finger Shape," updated material reflecting evolutions in Fraser's technical and pedagogical thinking, a "cleaner and leaner" literary style, and more extensive, better-organized tables of contents, with cross-references to corresponding chapters in the DVD. For more information please visit www.maplegroveproductions.com, www.craftofpiano.com, or www.alanfraser.net

Norepinephrine is a chemical neurotransmitter. Drugs that directly manipulate central nervous system (CNS) norepinephrine are being developed targeting noradrenergic neurons to deliver therapeutic effects. Noradrenergic drugs have been proven effective for depression and ADHD, and new disease indications are being identified. A team of experts provides the reader with a thorough understanding of the anatomy, physiology, molecular biology, pharmacology and therapeutics of norepinephrine in the brain, including an extensive review of the role of norepinephrine in brain diseases. The book is divided into four sections: the basic biology of norepinephrine; the role that norepinephrine plays in behavior; evidence of norepinephrine's role in CNS diseases, and the pharmacology and therapeutics of noradrenergic drugs in the treatment of psychiatric and neurological disorders.

In The Craft of Piano Playing, master pianist Alan Fraser offers readers an original and comprehensive approach to piano technique, offering over 100 illustrations and a series of unique exercises to guide the reader. Drawing on his many years as a performer and teacher, his long-standing collaborations with pedagogue Phil Cohen and virtuoso Kemal Gekich, and his professional training in the Feldenkrais Method, Fraser introduces his truly innovative piano technique by * Teaching how to move your hands with greater sensitivity, power, and accuracy, and honing the skeletal alignments to help you access your innate, structural potency; * Linking your physical technique to musical expression, creating an "absolutely natural way of moving at the piano that is powerful, flexible, and musical" (Piano News, Germany); and * Keeping your hands healthy while avoiding the threats of tendonitis, carpal tunnel syndrome, focal dystonia, and RSI. This revised second edition joins the DVD of the same name, his study guide, and his latest book, Honing the Pianistic Self-Image, in Alan Fraser's growing line of piano pedagogical materials. This edition includes new chapters, such as "Arm Rhythm" and "The Body's Support of Natural Finger Shape," updated material reflecting evolutions in Fraser's technical and pedagogical thinking, a "cleaner and leaner" literary style, and more extensive, better-organized tables of contents, with cross-references to corresponding chapters in the DVD. For more information please visit www.maplegroveproductions.com, www.craftofpiano.com, or www.alanfraser.net