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The focus of this symposium was on the present and future
capabilities of flow cytometry for both medical and biological
applications in cancer. This technology began with quite modest
instrumentation, with limited capabilities to answer biological
questions. Today, both the clinical workhorses and the powerful
multi-laser, multi-detector, sorting machinery, coupled with
sophisticated computers and storage devices and the increasing
storehouse of markers and dyes, are taking us to the limit and
beyond in finding answers to the cause and cure of cancer. In the
past, both normal hematopoietic tissue and leukemias have been the
tissue samples of choice in the application of flow cytometry, and
some of the most recent applications with these tissues are
presented here. However, the book also discusses the increasingly
sophisticated disaggregation techniques which allow investigators
the possibility to train their lasers on solid tumors. Not only can
we use flow cytometry with associated fluorescent markers to
understand the biology of cancer, but also the wide array of
existing and developing markers provides us with important
diagnostic tools in the detection of cancer early in either the
malignant or relapse process. And the field comes full circle, with
the use of the technology for gene mapping and other genetic
studies to unlock the basic malignant process.
The focus of this symposium was on the present and future
capabilities of flow cytometry for both medical and biological
applications in cancer. This technology began with quite modest
instrumentation, with limited capabilities to answer biological
questions. Today, both the clinical workhorses and the powerful
multi-laser, multi-detector, sorting machinery, coupled with
sophisticated computers and storage devices and the increasing
storehouse of markers and dyes, are taking us to the limit and
beyond in finding answers to the cause and cure of cancer. In the
past, both normal hematopoietic tissue and leukemias have been the
tissue samples of choice in the application of flow cytometry, and
some of the most recent applications with these tissues are
presented here. However, the book also discusses the increasingly
sophisticated disaggregation techniques which allow investigators
the possibility to train their lasers on solid tumors. Not only can
we use flow cytometry with associated fluorescent markers to
understand the biology of cancer, but also the wide array of
existing and developing markers provides us with important
diagnostic tools in the detection of cancer early in either the
malignant or relapse process. And the field comes full circle, with
the use of the technology for gene mapping and other genetic
studies to unlock the basic malignant process.
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