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This book covers all aspects of chronic radiation syndrome (CRS)
based on observations in a unique sample of residents of the Techa
riverside villages in the southern Urals who were exposed to
radioactive contamination in the 1950s owing to releases of liquid
radioactive wastes. The opening chapters discuss the definition and
classification of CRS, its epidemiology and pathogenesis and the
pathoanatomy of CRS during the development and recovery stages.
Clinical manifestations of CRS at the different stages are then
described in detail and the dynamics of hematopoietic changes are
thoroughly examined. In the following chapters, principles of
diagnosis and differential diagnosis are discussed and current and
potential treatment options, described. The medical and social
rehabilitation of persons with CRS is also covered. This book,
which casts new light on the condition, will be of value for all
practitioners and researchers with an interest in CRS.
This book covers all aspects of chronic radiation syndrome (CRS)
based on observations in a unique sample of residents of the Techa
riverside villages in the southern Urals who were exposed to
radioactive contamination in the 1950s owing to releases of liquid
radioactive wastes from Mayak Production Association, which
produced plutonium for weapons. In total, 940 cases of CRS were
diagnosed in this population and these patients were subjected to
detailed analysis. The opening chapters address the definition and
classification of CRS, epidemiology and pathogenesis, covering
molecular and cellular mechanisms, radioadaptation, and the role of
tissue reactions. The pathoanatomy of CRS during the development
and recovery stages is discussed for all organ systems. Clinical
manifestations of CRS at the different stages are then described in
detail and the dynamics of hematopoietic changes are thoroughly
examined. In the following chapters, principles of diagnosis
(including assessment of the exposure doses to critical organs) and
differential diagnosis from a wide range of other conditions are
discussed and current and potential treatment options, described.
The medical and social rehabilitation of persons with CRS is also
covered. This book, which casts new light on the condition, will be
of value for all practitioners and researchers with an interest in
CRS.
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