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Protein Physics is a lively presentation of the most general
problems of protein structure, folding and function from the
physics and chemistry perspective, based on lectures given by the
authors. It deals with fibrous, membrane and, most of all, with the
best studied water-soluble globular proteins, in both their native
and denatured states. The major aspects of protein physics are
covered systematically, physico-chemical properties of polypeptide
chains; their secondary structures; tertiary structures of proteins
and their classification; conformational transitions in protein
molecules and their folding; intermediates of protein folding;
folding nuclei; physical backgrounds of coding the protein
structures by their amino acid sequences and protein functions in
relation to the protein structure. The book will be of interest to
undergraduate and graduate level students and researchers of
biophysics, biochemistry, biology and material science.
Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry.
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