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This book combines the current knowledge on the role of lipids in
stem cell pluripotency and differentiation. It showcases various
approaches to the study of lipids and focuses on various types of
stem cells and specific lipids driving maintenance or
differentiation. The volume includes chapters reviewing roles of
specific lipids in pluripotency, neurogenesis and exocytosis as
well as in cancer stem cells. Examples of different classes of
lipids-such as sphingolipids, lysophospholipids, cannabinoids and
neutral lipids-are described and illustrate the vast biological
effects of this class of molecules. The international contributors
are all recognized experts in their respective fields. Covering the
various aspects of the topic, Lipidomics of Stem Cells provides an
up-to-date snapshot-unique among the literature-of where the lipid
world is in terms of understanding the roles of lipids in stem cell
biology. It provides an essential reference for stem cell
biologists, lipid biologists, development biologists, students,
academics and clinicians in related areas.
This fully updated edition explores methods involving
sphingosine-1-phosphate (S1P), a bioactive lysophospholipid which
has become the focus of much research interest as it has widespread
developmental and physio-pathological actions, controlling events
within the nervous, reproductive, gastrointestinal, vascular,
respiratory, and immune systems, in addition to having a prominent
role in cancer, early mammalian embryogenesis, and stem cells.
Here, worldwide experts in the S1P field describe in-depth
techniques in an array of cell types and with various physiological
applications, showcasing the important effects of S1P in
development and in physiopathology. As a volume in the Methods in
Molecular Biology series, chapters contain introductions to their
respective topics, lists of the relevant materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
for troubleshooting and avoiding known pitfalls. Authoritative and
timely, Sphingosine-1-Phosphate: Methods and Protocols, Second
Edition is another key resource for scientists working in this
fast-moving and dynamic field.
This book combines the current knowledge on the role of lipids in
stem cell pluripotency and differentiation. It showcases various
approaches to the study of lipids and focuses on various types of
stem cells and specific lipids driving maintenance or
differentiation. The volume includes chapters reviewing roles of
specific lipids in pluripotency, neurogenesis and exocytosis as
well as in cancer stem cells. Examples of different classes of
lipids-such as sphingolipids, lysophospholipids, cannabinoids and
neutral lipids-are described and illustrate the vast biological
effects of this class of molecules. The international contributors
are all recognized experts in their respective fields. Covering the
various aspects of the topic, Lipidomics of Stem Cells provides an
up-to-date snapshot-unique among the literature-of where the lipid
world is in terms of understanding the roles of lipids in stem cell
biology. It provides an essential reference for stem cell
biologists, lipid biologists, development biologists, students,
academics and clinicians in related areas.
This text is a comprehensive look at the current knowledge on stem
cell application for vision loss, showcasing different types of
stem cells (adult, embryonic, iPSCs) for diseases of the front and
the back of the eye. It also highlights data obtained in various
models from fish to human, as well as from the bionic eye project
for vision regeneration. This volume in the Stem Cell Biology and
Regenerative Medicine series is essential reading for stem cell
biologists, ophthalmologists, advanced and graduate students, in
addition to academics and medical staff who work in these
disciplines.
Sphingosine-1-phosphate is a bioactive lysophospholipid which has
become, in recent years, the focus of much research interest as it
has widespread developmental and physio-pathological actions,
controlling events within the nervous, reproductive,
gastrointestinal, vascular, respiratory, and immune systems, in
addition to having a prominent role in cancer, early mammalian
embryogenesis, and stem cells. In Sphingosine-1-Phosphate: Methods
and Protocols, worldwide experts in the S1P field describe in-depth
techniques in an array of cell types and with various physiological
applications, showcasing the important effects of S1P in
development and in physiopathology. As a volume in the Methods in
Molecular Biology (TM) series, chapters contain introductions to
their respective topics, lists of the relevant materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips for troubleshooting and avoiding known pitfalls.
Authoritative and timely, Sphingosine-1-Phosphate: Methods and
Protocols is a key resource for scientists working in this
expanding and dynamic field.
This text is a comprehensive look at the current knowledge on stem
cell application for vision loss, showcasing different types of
stem cells (adult, embryonic, iPSCs) for diseases of the front and
the back of the eye. It also highlights data obtained in various
models from fish to human, as well as from the bionic eye project
for vision regeneration. This volume in the Stem Cell Biology and
Regenerative Medicine series is essential reading for stem cell
biologists, ophthalmologists, advanced and graduate students, in
addition to academics and medical staff who work in these
disciplines.
Sphingosine-1-phosphate is a bioactive lysophospholipid which has
become, in recent years, the focus of much research interest as it
has widespread developmental and physio-pathological actions,
controlling events within the nervous, reproductive,
gastrointestinal, vascular, respiratory, and immune systems, in
addition to having a prominent role in cancer, early mammalian
embryogenesis, and stem cells. In Sphingosine-1-Phosphate: Methods
and Protocols, worldwide experts in the S1P field describe in-depth
techniques in an array of cell types and with various physiological
applications, showcasing the important effects of S1P in
development and in physiopathology. As a volume in the Methods in
Molecular Biology (TM) series, chapters contain introductions to
their respective topics, lists of the relevant materials and
reagents, step-by-step, readily reproducible laboratory protocols,
and tips for troubleshooting and avoiding known pitfalls.
Authoritative and timely, Sphingosine-1-Phosphate: Methods and
Protocols is a key resource for scientists working in this
expanding and dynamic field.
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