Published in honor of the sixty-fifth birthday of Professor Ingram Olkin of Stanford University. Part I contains a brief biography of Professor Olkin and an interview with him discussing his career and his research interests. Part II contains 32 technical papers written in Professor Olkin's honor by his collaborators, colleagues, and Ph.D. students. These original papers cover a wealth of topics in mathematical and applied statistics, including probability inequalities and characterizations, multivariate analysis and association, linear and nonlinear models, ranking and selection, experimental design, and approaches to statistical inference. The volume reflects the wide range of Professor Olkin's interests in and contributions to research in statistics, and provides an overview of new developments in these areas of research.