Acres of Skin sheds light on a dark episode in American medical history. From the mid-1950s to the mid-1970s, inmates at Philadelphia's Holmesburg Prison were used, in exchange for a few dollars, as guinea pigs in a host of medical experiments. Drawing on in-depth interviews with dozens of prisoners as well as the doctors and prison officials who, respectively, performed and enforced these tests, Allen M. Hornblum paints a harrowing portrait of medical abuse, moral indifference, and stark greed.
Acres of Skin raises provocative questions about human rights, prison treatment, and medical and research ethics as he exposes what really happened behind the locked doors of this American prison. The book answers the question: were there other prisons like this?

From the mid-1950s through the mid-1970s, inmates of Philadelphia's Holmesburg Prison were used, in exchange for a few dollars, as guinea pigs in a host of medical experiments. Hornblum paints a disturbing portrait of abuse, moral indifference, and greed, as doctors, in conjunction with the University of Pennsylvania and prison officials, established the prison as a testing lab.

From 1951 until 1974, Holmesburg Prison in Philadelphia was the site of thousands of experiments on prisoners conducted by researchers under the direction of University of Pennsylvania dermatologist Albert M. Kligman. While most of the experiments were testing cosmetics, detergents, and deodorants, the trials also included scores of Phase I drug trials, inoculations of radioactive isotopes, and applications of dioxin in addition to mind-control experiments for the Army and CIA. These experiments often left the subject-prisoners, mostly African Americans, in excruciating pain and had long-term debilitating effects on their health. This is one among many episodes of the sordid history of medical experimentation on the black population of the United States.

The story of the Holmesburg trials was documented by Allen Hornblum in his 1998 book Acres of Skin. The more general history of African Americans as human guinea pigs has most recently been told by Harriet Washington in her 2007 book Medical Apartheid. The subject is currently a topic of heated public debate in the wake of a 2006 report from an influential panel of medical experts recommending that the federal government loosen the regulations in place since the 1970s that have limited the testing of pharmaceuticals on prison inmates.

Sentenced to Science retells the story of the Holmesburg experiments more dramatically through the eyes of one black man, Edward "Butch" Anthony, who suffered greatly from the experiments for which he "volunteered" during multiple terms at the prison. This is not only one black man's highly personal account of what it was like to be an imprisoned test subject, but also a sobering reminder that there were many African Americans caught in the viselike grip of a scientific research community willing to bend any code of ethics in order to accomplish its goals and a criminal justice system that sold prisoners to the highest bidder.

Babe Ruth, Jack Dempsey, Bobby Jones, and Bill Tilden were the legendary quartet of the "Golden Age of Sports" in the 1920s. They transformed their respective athletic disciplines and captured the imagination of a nation. The indisputable force behind the emergence of professional tennis as a popular and lucrative sport, Tilden's on-court accomplishments are nothing short of staggering. The first American-born player to win Wimbledon and a seven-time winner of the U.S. singles championship, he was the number 1 ranked player for ten straight years. A tall, flamboyant player with a striking appearance, Tilden didn't just play; he performed with a singular style that separated him from other top athletes. Tilden was a showman off the court as well. He appeared in numerous comedies and dramas on both stage and screen and was a Renaissance man who wrote more than two dozen fiction and nonfiction books, including several successful tennis instructions books. But Tilden had a secret-one he didn't fully understand himself. After he left competitive tennis in the late 1940s, he faced a lurid fall from grace when he was arrested after an incident involving an underage boy in his car. Tilden served seven months in prison and later attempted to explain his questionable behavior to the public, only to be ostracized from the tennis circuit. Despite his glorious career in tennis, his final years were much constrained and lived amid considerable public shunning. Tilden's athletic accomplishments remain, as he is arguably the best American player ever. American Colossus is a thorough account of his life, bringing a much-needed look back at one of the world's greatest athletes and a person whose story is as relevant as ever.