Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries is a thorough review of the disease written by experts studying its detection and treatment. These state-of-the-art chapters summarize in a comprehensive manner emerging knowledge about this important area of medicine. The pathophysiology and treatment of peripheral artery (PAD) disease remains poorly understood even by practitioners.  Often it is assumed that PAD should be treated in a similar fashion to coronary artery disease (CAD) when in fact recent data suggest a distinct pathophysiology with genetic risk having some but not complete overlap with CAD.  This is a novel reference of emerging data on the factors behind its development and progression, detection, and treatment suggest an emerging paradigm for this disease.

Coronary Calcium: A Comprehensive Understanding of Its Biology, Use in Screening, and Interventional Management provides a comprehensive update on the current understanding of the significance of coronary artery calcification, showing the connection to the development of advanced atherosclerosis that will lead to better risk evaluations. Coverage includes information on the basic science behind the development of coronary calcium in atherosclerotic lesions, the pathology of calcified coronary lesions in humans, its differential development by race, and its relationship to plaque progression. Computed tomography is also covered to show the significance of coronary calcium for risk prediction and the potential role of various pharmacologic interventions. Each chapter contains summaries with salient and important points, making this book perfect for researchers and physicians interested in the field of vascular calcification.