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Oral cancer is one of the most prevalent cancers of the world. It
is among the top ten reasons to cause death. Oral cancer ranks one
among all the cancers caused among men, which represents 4% of all
deaths among men. In women it stands third among all cancers and
represent 2% of all deaths. Oral cancer due to its location in the
most accessible part of the body, i.e. the mouth it can be detected
in the early stages. However, because of lack of symptoms,
especially pain, it is neglected and often recognized at the
advanced stage thus a proper medical care is not reached in the
initial stage. Hence it is important for all the health
professionals to equip themselves with adequate knowledge to detect
this disease at early stage.
The regeneration of the periodontium can be distinguished from many
other regenerative processes because of the periodontium's
extremely limited endogenous regenerative capability. Additionally,
regeneration of the periodontium involves the regeneration of at
least three unique tissues and their complex structures. Recent
evidence suggests that periodontal ligament retains its
regenerative capacity to different degrees throughout adulthood
which is attributed to the remaining progenitor/stem cells within
the periodontium that maintain their proliferation and
differentiation potential and the regeneration of periodontal
tissues can be stimulated using growth factors and other host
modulating agents.
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