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Gerald Reaven, the discoverer of Syndrome X, and a panel of
world-class investigators thoughtfully summarize our current
understanding of how insulin resistance and its compensating
hyperinsulinemia play a major role in the pathogenesis and clinical
course of high blood pressure and cardiovascular disease-the
so-called diseases of Western civilization. These distinguished
authorities detail, for the first time, the pathophysiological
consequences and the clinical syndromes, excluding Type 2 diabetes,
related to insulin resistance. They also examine the genetic and
lifestyle factors that contribute to the wide differences in
insulin action that exist in the population at large. Timely and
authoritative, Insulin Resistance: The Metabolic Syndrome X
illuminates the full importance of insulin resistance as a major
cause of hypertension, heart disease, and polycystic ovary
syndrome.
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