DESCRIPTION Distributed systems are unpredictable, and it can be an enormous challenge to manage around potentially-crippling obstacles like hardware failures, unanticipated changes in load, and network issues. Amazon Web Services (AWS) is a platform for hosting distributed applications in a secure, flexible cloud environment. AWS provides a suite of services designed to keep the focus on what an application does instead of the infrastructure required to run it. Whether serving up blog pages, analyzing fast data in real-time, building software as a service, or implementing a massive e-commerce site, AWS provides both a stable platform and services that will scale with every application. Amazon Web Services in Action introduces readers to computing, storing, and networking in the AWS cloud. It starts with a broad overview of AWS, and shows how to spin up servers manually and from the command line. Then, it explores infrastructure automation with the AWS CloudFormation service, where readers can describe a blueprint of their infrastructure as code. Readers will learn how to isolate systems using private networks to increase security, how to use the most valuable AWS managed services available on AWS, and about the benefits of stateless servers. In the end, they'll look to the AWS model for high availability, scaling, decoupling with queues and load balancers, and fault tolerance. KEY SELLING POINTS Explains the key concepts of AWS Gives an overview of the most important services Allows readers to take full advantage of the AWS platform AUDIENCE Written for developers and DevOps engineers who are moving traditionally-deployed distributed applications to the AWS platform. No experience with AWS is required. ABOUT THE TECHNOLOGY Amazon Web Services is a platform of services in the Cloud to provide everything needed to run applications-from hosting a private blog, to running one of the biggest websites on earth, analyzing data for cancer research, or providing business applications.

Description Fully updated to include the latest revisions and updates to AWS; this new edition also offers three new chapters covering the latest additions to the AWS platform: serverless infrastructure automation with AWS Lambda, sharing data volumes between machines with EFS, and caching data in memory with ElastiCache! Amazon Web Services in Action, Second Edition is a comprehensive introduction to computing, storing, and networking in the AWS cloud. Readers will find clear, relevant coverage of all the essential AWS services they need to know, emphasizing best practices for security, high availability and scalability. Key features * Hands-on guide * Practical examples * Step-by-step instructions Audience Written for developers and DevOps engineers moving distributed applications to the AWS platform. About the technology AWS is known as a cloud computing platform. Cloud computing, or the cloud, is a metaphor for supply and consumption of IT resources. The IT resources in the cloud aren't directly visible to the user; there are layers of abstraction in between.

Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.

Master essential best practices for deploying and managing applications on Amazon Web Services. The ideal guide for mid-level developers, DevOps or platform engineers, architects, and system administrators. Amazon Web Services in Action: An in-depth guide to AWS is a comprehensive, practical introduction to deploying and managing applications on the AWS cloud platform. This revised bestseller is packed with techniques for building highly available and scalable architectures and automating deployment with Infrastructure as Code. This book will show you how to: Leverage globally distributed data centres to launch virtual machines with EC2 Store and archive large volumes of data with EBS, S3, and EFS Persist and query data with highly available and scalable database systems with RDS and DynamoDB Enhance performance with caching data in-memory with ElastiCache and MemoryDB Use Infrastructure as Code to automate your cloud infrastructure Secure workloads running in the cloud with VPC and IAM Build fault-tolerant web applications with ALB and SQS Automate common sysadmin tasks with Lambda, CLI, and SDK Build cloud-native applications based on containers with AppRunner, ECS, Fargate About the technology Thousands of developers have chosen Amazon Web Services in Action: An in-depth guide to AWS to help them succeed with the AWS cloud. Readers love this all-practical handbook for its complete introduction to computing, storage, and networking, along with best practices for all core AWS services. Amazon Web Services, the leading cloud computing platform, offers customers APIs for on-demand access to computing services. Rich in examples and best practices of how to use AWS, this Manning bestseller is now released in its third, revised, and improved edition.