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Andrew Arnold The past several years have been a time of intense
excitement and have brought major advances in the understanding and
treatment of endocrine neoplasms. This is therefore an excellent
point at which to undertake a broad based overview of the state of
the art in endocrine neoplasia for the Cancer Treatment and
Research series. Because of the wide and interdisciplinary
readership of this series, our aim for each chapter has been to
provide ample background for those not highly familiar with the
topic, while emphasizing the most recent advances. Furthermore, the
chapters have been written with the clinician in mind, whether she
or he is an oncologist, endocrinologist, surgeon, generalist,
pathologist, or radiologist. As such, the authors' mission has been
to focus on clinically relevant issues and to present the
scientific basis of current or potential future advances in a
manner easily digestible to the nonexpert. Endocrine tumors often
cause problems for the patient by virtue of their hormonal
activity, which may frequently (but certainly not always) over
shadow the adverse consequences related to their mass per se. In
fact, it is important to keep in mind that endocrine tumors can
manifest two biologically separable but often intertwined
properties, namely, increased cell mass and abnormal hormonal
function. These need not go hand in hand, and their distinction has
definite clinical relevance in, for example, the increasingly
recognized problem of incidentally discovered adrenal or pituitary
masses."
Carshalton in Surrey was deeply affected by the First World War:
over 1,900 local men enlisted to fight. Of those men, 243 lost
their lives and are commemorated on the war memorial. As we find
ourselves commemorating the centenary of the war, it is more
important than ever that these men are not forgotten. Drawing on
over six years of research, this book brings together the stories
of the lives - and deaths - of these men. Utilising a wide variety
of sources and complemented by many previously unseen photographs,
their stories are told here, from the fourteen sets of brothers who
were killed, to the devastating effect of the Somme campaign in
which nineteen local men lost their lives on the opening day alone.
Andrew Arnold The past several years have been a time of intense
excitement and have brought major advances in the understanding and
treatment of endocrine neoplasms. This is therefore an excellent
point at which to undertake a broad based overview of the state of
the art in endocrine neoplasia for the Cancer Treatment and
Research series. Because of the wide and interdisciplinary
readership of this series, our aim for each chapter has been to
provide ample background for those not highly familiar with the
topic, while emphasizing the most recent advances. Furthermore, the
chapters have been written with the clinician in mind, whether she
or he is an oncologist, endocrinologist, surgeon, generalist,
pathologist, or radiologist. As such, the authors' mission has been
to focus on clinically relevant issues and to present the
scientific basis of current or potential future advances in a
manner easily digestible to the nonexpert. Endocrine tumors often
cause problems for the patient by virtue of their hormonal
activity, which may frequently (but certainly not always) over
shadow the adverse consequences related to their mass per se. In
fact, it is important to keep in mind that endocrine tumors can
manifest two biologically separable but often intertwined
properties, namely, increased cell mass and abnormal hormonal
function. These need not go hand in hand, and their distinction has
definite clinical relevance in, for example, the increasingly
recognized problem of incidentally discovered adrenal or pituitary
masses.
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