This issue of Clinics in Chest Medicine focuses on Current Perspectives on the Diagnosis and Treatment of Fungal Chest Infections.Editors Andrew Limper and Eva Carmona have assembled an expert team of authors on topics such as: When to consider the possibility of a fungal infection: an overview of clinical diagnosis and laboratory approaches; Overview of treatment approaches for fungal infections; Clinical perspectives in the diagnosis and management of histoplasmosis; Presentation and management of coccidiodomycosis in immune competent and immunosuppressed patients; Clinical manifestations and treatment of blastomycosis; Update on the epidemiology, diagnosis, and treatment of cryptococcal infections; Approach to fungal infections in HIV-infected individuals: Pneumocystis and beyond; Fungal infections in immunocompromised patients with malignancies: practical approaches to prevention, diagnosis, and treatment; Candidemia in the intensive care unit; Fungal infections following lung transplantation; Noninvasive aspergillus infections and syndromes; Contemporary laboratory modalities for the diagnosis of fungal infections; Emergence of the molds other than Aspergillus in immunocompromised patients.