When people need healthcare, few worry about being harmed by someone from the medical team making a mistake. Unfortunately, mistakes do happen, and many of the adverse events are not only serious but also preventable. Many countries struggle with top-heavy systems, in which decisions are made about how care is provided by those who are far from experienced in caring for patients. This must change. Professionals at the sharp end need support, structure, and help organizing necessary information to create a safe culture, a learning environment, and safe patient care-all at lower costs. This handbook provides tools for designing a structure for a management system, as well as the tools for documenting processes within it. The starting point is based on current safety research. The book is designed for medical professionals, managers, project members, politicians, public officials, and executives-all who work with patient safety matters. The content shows a new way to healthcare management, presenting an alternative approach together with concrete advice on how healthcare executives and practitioners can begin to think and act differently in order to provide safe healthcare.