As telehealth and occupational therapy service delivery in early intervention become more common, occupational therapy practitioners have the opportunity to apply their flexibility, adaptability, and unique skill set to serve young children, regardless of physical location. This text, the second in a series on telehealth by AOTA, acknowledges that telehealth is a critical part of delivering occupational therapy in early intervention. It equips practitioners to effectively bridge the digital divide, ensure equitable access to services, determine whether telehealth is an appropriate fit, and coach caregivers for the best possible outcomes. Case examples illustrate how to apply content in realistic scenarios. Practical and evidence based, practitioners can immediately integrate information into their occupational therapy practice to support families.