This book constitutes the refereed proceedings of the 6th International Symposium on Leveraging Applications of Formal Methods, Verification, and Validation, ISoLA 2014, held in Corfu, Greece, in October 2014, and the 5th International Symposium, ISoLA 2012, held in Heraklion, Crete, Greece, in October 2012. The 9 revised full papers presented were carefully reviewed and selected from 22 submissions. This volume combines the post-conference proceedings of the 2014 Doctoral Symposium and the 2014 Tutorial "Automata Learning in Practice" with the post-conference publication of selected contributions from the Tracks "Process-Oriented Geoinformation Systems and Applications" and "Processes and Data Integration in the Networked Healthcare" of ISoLA 2012.

This book contains the refereed proceedings of the 7th International Conference on Software Business, ICSOB 2016, held in Ljubljana, Slovenia, in June 2016. Software business refers to commercial activities in and around the software industry aimed at generating income from the delivery of software products and services. The theme of the event was "Software as a New Way of Providing Cutting-edge Solutions". The 10 full and 5 short papers for ICSOB were selected from 38 submissions. The papers span a wide range of issues related to contemporary software business, ranging from strategic aspects to operational challenges. The strong presence of software ecosystem papers confirms the importance of this topic and influence on software business. In addition, a short abstract of the key note by Peter Lick and Hans-Bernd Kittlaus is also included.

This book presents an agile and model-driven approach to manage scientific workflows. The approach is based on the Extreme Model Driven Design (XMDD) paradigm and aims at simplifying and automating the complex data analysis processes carried out by scientists in their day-to-day work. Besides documenting the impact the workflow modeling might have on the work of natural scientists, this book serves three major purposes: 1. It acts as a primer for practitioners who are interested to learn how to think in terms of services and workflows when facing domain-specific scientific processes. 2. It provides interesting material for readers already familiar with this kind of tools, because it introduces systematically both the technologies used in each case study and the basic concepts behind them. 3. As the addressed thematic field becomes increasingly relevant for lectures in both computer science and experimental sciences, it also provides helpful material for teachers that plan similar courses.

The continuous trend in computer science to lift programming to higher abstraction levels increases scalability and opens programming to a wider public. In particular, service-oriented programming and the support of semantics-based frameworks make application development accessible to users with almost no programming expertise. This monograph establishes requirement-centric scientific workflow design as an instance of consequent constraint-driven development. Requirements formulated in terms of user-level constraints are automatically transformed into running applications using temporal logic-based synthesis technology. The impact of this approach is illustrated by applying it to four very different bioinformatics scenarios: phylogenetic analysis, the dedicated GeneFisher-P scenario, the FiatFlux-P scenario, and microarray data analyses.