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The book starts with dissecting mechanisms underlying viral immune
evasion via exploiting the host complement system by vaccinia
virus, and by modulating the type 1 interferon response by RNA
viruses. Yet another chapter looks into how viroporins expressed by
different families of viruses causing influenza A virus, SARS,
hepatitis C and HIV interact with several cellular pathways.
Understanding of these mechanisms can aid the development of novel
potential anti viral targets. The chapter on tuberculosis discusses
the emerging importance of the innate immune mechanisms against
Mycobacterium tuberculosis infection and latency. This book has a
strong focus on fungal pathogenesis and immunity, starting with
virulence and host factors that attain great importance in
candidiasis and associated escape tricks ofseriously opportunistic
fungi. Two chapters on Aspergillus fumigatus elaborate on the
pathogenic mechanisms: first discussing A. fumigatus airway
epithelium interaction, followed by fungal and host factors that
are paramount in the development of allergic and invasive
aspergillosis. In the subsequent chapter, there is a general
discussion on the innate and adaptive immune responses against
primary and opportunistic fungal pathogens."
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