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Imagine scientists controlling the transmission of certain diseases through the genetic modification of mosquitoes. Eradicating harmful insects without the use of pesticides. Or increasing the fertility of some insects who in turn eat harmful arthropods or even a plant pathogen. Those are just a few of the real-world applications of insect transgenesis, which offers substantial benefits to humankind-whether it be in improving agricultural productivity or reducing the spread of insect-vectored diseases. Insect Transgenesis: Methods and Applications is the first publication to describe in a comprehensive manner the various methodologies available, possible applications, and the risk assessment and regulatory issues involved in this fascinating area of research. Divided into several areas of interest, the book starts with an overview of the history and methodology of insect gene transfer. The book then examines gene targeting by homologous recombination and recombination systems, and systems for transgenic selection, including visible eye color markers, chemical resistance, and fluorescent proteins. Other sections consider the use of various vector systems to integrate DNA into a host genome or to express foreign genes in a host organism. The work concludes with strategies for the use of transgenic insects, including examples for agricultural pests and vectors of disease. Of particular interest are the final chapters that discuss risk assessment considerations and governmental regulatory procedures for the transport and release of transgenic insects.
Imagine scientists controlling the transmission of certain diseases
through the genetic modification of mosquitoes. Eradicating harmful
insects without the use of pesticides. Or increasing the fertility
of some insects who in turn eat harmful arthropods or even a plant
pathogen. Those are just a few of the real-world applications of
insect transgenesis, which offers substantial benefits to
humankind-whether it be in improving agricultural productivity or
reducing the spread of insect-vectored diseases. Insect
Transgenesis: Methods and Applications is the first publication to
describe in a comprehensive manner the various methodologies
available, possible applications, and the risk assessment and
regulatory issues involved in this fascinating area of research.
Divided into several areas of interest, the book starts with an
overview of the history and methodology of insect gene transfer.
The book then examines gene targeting by homologous recombination
and recombination systems, and systems for transgenic selection,
including visible eye color markers, chemical resistance, and
fluorescent proteins. Other sections consider the use of various
vector systems to integrate DNA into a host genome or to express
foreign genes in a host organism. The work concludes with
strategies for the use of transgenic insects, including examples
for agricultural pests and vectors of disease. Of particular
interest are the final chapters that discuss risk assessment
considerations and governmental regulatory procedures for the
transport and release of transgenic insects.
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