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Anesthetics produce a reversible state of unconsciousness
accompanied by ante- grade amnesia. This remarkable phenomenon
brings great relief to surgical patients and wonder to clinicians
and scientists. To date, we do not fully understand the mechanisms
by which anesthetics ablate conscious sensation and memory. We are,
however, making progress. This book presents original results as
well as overviews of the current state of knowledge of the problem.
It is authored by investigators who know the ?eld well; their
research at a number of levels has contributed substantially to our
c- rent understanding of anesthetic modulation of memory and
consciousness. Most of the contributors were presenters at two
workshops organized by Dr. Pearce and Dr. Hudetz at the 40th Annual
Winter Conference on Brain Research, held at Snowmass Village,
Colorado, from January 27 through February 2, 2007. One workshop
focused on anesthetic modulation of consciousness and another on
an- thetic modulation of memory. Seven of the chapters are based on
material presented at these symposia - appropriately updated with
new relevant ?ndings. This infor- tion is supplemented by chapters
on anesthesia and sleep, computational analysis of the state of
anesthesia, and the clinical phenomenon of "anesthesia awareness,"
a topic that has recently received much public attention. With
these three additional contributions, the book thus includes 10
chapters.
Anesthetics produce a reversible state of unconsciousness
accompanied by ante- grade amnesia. This remarkable phenomenon
brings great relief to surgical patients and wonder to clinicians
and scientists. To date, we do not fully understand the mechanisms
by which anesthetics ablate conscious sensation and memory. We are,
however, making progress. This book presents original results as
well as overviews of the current state of knowledge of the problem.
It is authored by investigators who know the ?eld well; their
research at a number of levels has contributed substantially to our
c- rent understanding of anesthetic modulation of memory and
consciousness. Most of the contributors were presenters at two
workshops organized by Dr. Pearce and Dr. Hudetz at the 40th Annual
Winter Conference on Brain Research, held at Snowmass Village,
Colorado, from January 27 through February 2, 2007. One workshop
focused on anesthetic modulation of consciousness and another on
an- thetic modulation of memory. Seven of the chapters are based on
material presented at these symposia - appropriately updated with
new relevant ?ndings. This infor- tion is supplemented by chapters
on anesthesia and sleep, computational analysis of the state of
anesthesia, and the clinical phenomenon of "anesthesia awareness,"
a topic that has recently received much public attention. With
these three additional contributions, the book thus includes 10
chapters.
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